Individual specific variable drug response against similar drugs raises a significant
challenge for the effective and safe treatment of many human diseases. Pharmacogenomics …

Pharmacogenomics (PGx) is often promoted as the domain of precision medicine with the
greatest potential to readily impact everyday healthcare. Rapid advances in PGx knowledge …

Adverse drug reactions (ADR) represent a significant contributor to morbidity and mortality,
imposing a substantial financial burden. Genetic ancestry plays a crucial role in drug …

Introduction Racial and ethnic categories are frequently used in pharmacogenetics literature
to stratify patients; however, these categories can be inconsistent across different studies. To …

While genomic approaches to precision medicine hold great promise, they remain
prohibitively expensive for develo** countries. The precision public health paradigm …

Recent studies have pointed out the essential role of genetic ancestry in population
pharmacogenetics. In this study, we analyzed the whole-genome sequencing data from The …

Introduction: Investigating variation in genes involved in the absorption, distribution,
metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic …

Genetic variations have an established impact on the pharmacological response.
Investigating this variation resulted in a compilation of variants in “pharmacogenes”. The …

Pharmacogenomics aims to tailor pharmacological treatment to each individual by
considering associations between genetic polymorphisms and adverse drug effects (ADEs) …

Genetic ancestry plays a major role in pharmacogenomics, and a deeper understanding of
the genetic diversity among individuals holds immerse promise for resha** personalized …