Adenosine, caffeine, and sleep–wake regulation: state of the science and perspectives

CF Reichert, T Deboer, HP Landolt - Journal of sleep research, 2022 - Wiley Online Library
For hundreds of years, mankind has been influencing its sleep and waking state through the
adenosinergic system. For~ 100 years now, systematic research has been performed, first …

[HTML][HTML] Self-reported sleep duration and cognitive performance in older adults: a systematic review and meta-analysis

JC Lo, JA Groeger, GH Cheng, DJ Dijk, MWL Chee - Sleep medicine, 2016 - Elsevier
Sleep is important for optimal cognitive functioning across the lifespan. Among older adults
(≥ 55 years), self-reported short and long sleep durations have been repeatedly, albeit …

The two‐process model of sleep regulation: a reappraisal

AA Borbély, S Daan, A Wirz‐Justice… - Journal of sleep …, 2016 - Wiley Online Library
In the last three decades the two‐process model of sleep regulation has served as a major
conceptual framework in sleep research. It has been applied widely in studies on fatigue …

Pupil diameter covaries with BOLD activity in human locus coeruleus

PR Murphy, RG O'connell, M O'sullivan… - Human brain …, 2014 - Wiley Online Library
The locus coeruleus‐noradrenergic (LC–NA) neuromodulatory system has been implicated
in a broad array of cognitive processes, yet scope for investigating this system's function in …

[HTML][HTML] Sleep homeostasis and the circadian clock: do the circadian pacemaker and the sleep homeostat influence each other's functioning?

T Deboer - Neurobiology of sleep and circadian rhythms, 2018 - Elsevier
Sleep is regulated by a homeostatic and a circadian process. Together these two processes
determine most aspects of sleep and related variables like sleepiness and alertness. The …

Sustaining attention to simple tasks: a meta-analytic review of the neural mechanisms of vigilant attention.

R Langner, SB Eickhoff - Psychological bulletin, 2013 - psycnet.apa.org
Maintaining attention for more than a few seconds is essential for mastering everyday life.
Yet, our ability to stay focused on a particular task is limited, resulting in well-known …

Individual differences in light sensitivity affect sleep and circadian rhythms

SL Chellappa - Sleep, 2021 - academic.oup.com
Artificial lighting is omnipresent in contemporary society with disruptive consequences for
human sleep and circadian rhythms because of overexposure to light, particularly in the …

Circadian rhythms, sleep deprivation, and human performance

N Goel, M Basner, H Rao, DF Dinges - Progress in molecular biology and …, 2013 - Elsevier
Much of the current science on, and mathematical modeling of, dynamic changes in human
performance within and between days is dominated by the two-process model of sleep …

Pupillometry and P3 index the locus coeruleus–noradrenergic arousal function in humans

PR Murphy, IH Robertson, JH Balsters… - …, 2011 - Wiley Online Library
The adaptive gain theory highlights the pivotal role of the locus coeruleus–noradrenergic
(LC‐NE) system in regulating task engagement. In humans, however, LC‐NE functional …

Effects of sleep and circadian rhythm on the human immune system

T Lange, S Dimitrov, J Born - Annals of the New York Academy …, 2010 - Wiley Online Library
Many immune parameters show systematic fluctuations over the 24‐h day in human blood.
Circulating naive T‐cells and production of proinflammatory cytokines, like interleukin‐12 (IL …