Cytokines and chemokines in cerebral malaria pathogenesis

J Dunst, F Kamena, K Matuschewski - Frontiers in cellular and …, 2017 - frontiersin.org
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …

Evidence and implications of mortality associated with acute Plasmodium vivax malaria

JK Baird - Clinical microbiology reviews, 2013 - journals.asm.org
Vivax malaria threatens patients despite relatively low-grade parasitemias in peripheral
blood. The tenet of death as a rare outcome, derived from antiquated and flawed clinical …

Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation

P Brasil, MG Zalis, A de Pina-Costa… - The Lancet Global …, 2017 - thelancet.com
Background Malaria was eliminated from southern and southeastern Brazil over 50 years
ago. However, an increasing number of autochthonous episodes attributed to Plasmodium …

Clinical aspects of uncomplicated and severe malaria

A Bartoloni, L Zammarchi - Mediterranean journal of …, 2012 - pmc.ncbi.nlm.nih.gov
The first symptoms of malaria, common to all the different malaria species, are nonspecific
and mimic a flu-like syndrome. Although fever represents the cardinal feature, clinical …

Thousands of chemical starting points for antimalarial lead identification

FJ Gamo, LM Sanz, J Vidal, C De Cozar, E Alvarez… - Nature, 2010 - nature.com
Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug
resistance is widespread, no new chemical class of antimalarials has been introduced into …

A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010

PW Gething, IRF Elyazar, CL Moyes, DL Smith… - 2012 - journals.plos.org
Background Current understanding of the spatial epidemiology and geographical
distribution of Plasmodium vivax is far less developed than that for P. falciparum …

Parasite recognition and signaling mechanisms in innate immune responses to malaria

DC Gowda, X Wu - Frontiers in immunology, 2018 - frontiersin.org
Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

I Mueller, MR Galinski, JK Baird, JM Carlton… - The Lancet infectious …, 2009 - thelancet.com
Plasmodium vivax is geographically the most widely distributed cause of malaria in people,
with up to 2· 5 billion people at risk and an estimated 80 million to 300 million clinical cases …

Clinical impact of vivax malaria: a collection review

AP Phyo, P Dahal, M Mayxay, EA Ashley - PLoS Medicine, 2022 - journals.plos.org
Background Plasmodium vivax infects an estimated 7 million people every year. Previously,
vivax malaria was perceived as a benign condition, particularly when compared to …

Geographical variation in Plasmodium vivax relapse

KE Battle, MS Karhunen, S Bhatt, PW Gething… - Malaria journal, 2014 - Springer
Background Plasmodium vivax has the widest geographic distribution of the human malaria
parasites and nearly 2.5 billion people live at risk of infection. The control of P. vivax in …