Tumors are comprised of both cancer cells and surrounding stromal components. As an
essential part of the tumor microenvironment, the tumor stroma is highly dynamic …

Metabolomics and artificial intelligence (AI) form a synergistic partnership. Metabolomics
generates large datasets comprising hundreds to thousands of metabolites with complex …

Background: Cancer-derived extracellular vesicles (EVs) are regarded to have significant
function in most steps during cancer progression. This meta-analysis aims to investigate the …

Simple Summary Prostate cancer is a malignancy that affects a high number of men all over
the world. When indolent, prostate cancer can remain silent for years without needing …

The cellular microenvironment composition and changes therein play an extremely
important role in cancer development. Changes in the extracellular matrix (ECM), which …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. New
tools which can aid in the understanding of PDAC biology and novel drug development are …

Simple Summary Breast cancer ranks as the most prevalent cancer among women. Current
screening includes regular mammography and subsequent biopsy if the mammography …

The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

Background Gastric cancer is one of the deadliest cancers, currently available therapies
have limited success. Cancer-associated fibroblasts (CAFs) are pivotal cells in the stroma of …

Substantial improvement in prognosis among metastatic renal cell carcinoma (mRCC)
patients has been achieved, owing to the rapid development and utilization of …