Protective effects of PACAP in peripheral organs

D Toth, E Szabo, A Tamas, T Juhasz… - Frontiers in …, 2020 - frontiersin.org
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide widely
distributed in the nervous system, where it exerts strong neuroprotective effects. PACAP is …

PACAP is an endogenous protective factor—insights from PACAP-deficient mice

D Reglodi, P Kiss, K Szabadfi, T Atlasz… - Journal of Molecular …, 2012 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a widespread neuropeptide
with a diverse array of biological functions. Not surprisingly, the lack of endogenous PACAP …

Protective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) against apoptosis

T Seaborn, O Masmoudi-Kouli… - Current …, 2011 - ingentaconnect.com
Apoptosis is a regulated process leading to cell death, which is implicated both in normal
development and in various pathologies including heart failure, stroke and …

Role of PACAP in ischemic neural death

H Ohtaki, T Nakamachi, K Dohi, S Shioda - Journal of Molecular …, 2008 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that was first
isolated from an ovine hypothalamus in 1989. Since its discovery, more than 2,000 papers …

Protective effects of PACAP in ischemia

D Reglodi, A Vaczy, E Rubio-Beltran… - The Journal of …, 2018 - Springer
Pituitary adenylate cyclase activating polypeptide (PACAP) is an ubiquitous peptide
involved, among others, in neurodevelopment, neuromodulation, neuroprotection …

Effect of PACAP in central and peripheral nerve injuries

A Tamas, D Reglodi, O Farkas, E Kovesdi, J Pal… - International journal of …, 2012 - mdpi.com
Pituitary adenylate cyclase activating polypeptide (PACAP) is a bioactive peptide with
diverse effects in the nervous system. In addition to its more classic role as a …

Differences in pituitary adenylate cyclase-activating peptide and calcitonin gene-related peptide release in the trigeminovascular system

JCA Edvinsson, AS Grell, K Warfvinge… - …, 2020 - journals.sagepub.com
Background Several neurotransmitters are expressed in the neurons of the trigeminal
ganglion. One such signalling molecule is the pituitary adenylate cyclase-activating peptide …

[HTML][HTML] Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo

S Seeliger, J Buddenkotte… - The American journal of …, 2010 - Elsevier
Pituitary adenylate cyclase-activating peptide (PACAP) is an important neuropeptide and
immunomodulator in various tissues. Although this peptide and its receptors (ie, VPAC1R …

PACAP-38 and PAC1 receptor alterations in plasma and cardiac tissue samples of heart failure patients

D Szabó, Z Sárszegi, B Polgár, É Sághy… - International Journal of …, 2022 - mdpi.com
Pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) is a multifunctional
neuropeptide, which may play a role in cardioprotection. However, little is known about the …

Multimodal neuroprotection induced by PACAP38 in oxygen–glucose deprivation and middle cerebral artery occlusion stroke models

P Lazarovici, G Cohen, H Arien-Zakay, J Chen… - Journal of molecular …, 2012 - Springer
Pituitary adenylate cyclase activating peptide (PACAP), a potent neuropeptide which
crosses the blood–brain barrier, is known to provide neuroprotection in rat stroke models of …