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Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …
metabolites and their availability in the gut and other organs is determined by environmental …
The metabolic nature of inflammatory bowel diseases
TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022 - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
The current and future perspectives of postbiotics
B Liang, D **_microglial_function_by_gating_glycolytic_flux_and_mitochondrial_activity/links/6548fb22b86a1d521bbfa4f8/Dual-roles-of-hexokinase-2-in-sha**-microglial-function-by-gating-glycolytic-flux-and-mitochondrial-activity.pdf" data-clk="hl=nl&sa=T&oi=gga&ct=gga&cd=3&d=14316708164265841888&ei=pXS8Z8WoJtjGieoP9s7J0As" data-clk-atid="4BQA5Dgqr8YJ" target="_blank">[PDF] researchgate.net
Dual roles of hexokinase 2 in sha** microglial function by gating glycolytic flux and mitochondrial activity
Microglia continuously survey the brain parenchyma and actively shift status following
stimulation. These processes demand a unique bioenergetic programme; however, little is …
stimulation. These processes demand a unique bioenergetic programme; however, little is …
Degradation of hexokinase 2 blocks glycolysis and induces GSDME-dependent pyroptosis to amplify immunogenic cell death for breast cancer therapy
R Sang, R Fan, A Deng, J Gou, R Lin… - Journal of Medicinal …, 2023 - ACS Publications
Hexokinase 2 (HK2) is the principal rate-limiting enzyme in the aerobic glycolysis pathway
and determines the quantity of glucose entering glycolysis. However, the current HK2 …
and determines the quantity of glucose entering glycolysis. However, the current HK2 …
Cancer immunometabolism: advent, challenges, and perspective
Q Dang, B Li, B **, Z Ye, X Lou, T Wang, Y Wang… - Molecular Cancer, 2024 - Springer
For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …
Clostridium butyricum and carbohydrate active enzymes contribute to the reduced fat deposition in pigs
L Ma, S Tao, T Song, W Lyu, Y Li, W Wang, Q Shen… - Imeta, 2024 - Wiley Online Library
Pig gastrointestinal tracts harbor a heterogeneous and dynamic ecosystem populated with
trillions of microbes, enhancing the ability of the host to harvest energy from dietary …
trillions of microbes, enhancing the ability of the host to harvest energy from dietary …
[HTML][HTML] Macrophage metabolism reprogramming EGCG-Cu coordination capsules delivered in polyzwitterionic hydrogel for burn wound healing and regeneration
Excessive reactive oxygen species (ROS) at severe burn injury sites may promote metabolic
reprogramming of macrophages to induce a deteriorative and uncontrolled inflammation …
reprogramming of macrophages to induce a deteriorative and uncontrolled inflammation …
[HTML][HTML] The role of microbiota-mitochondria crosstalk in pathogenesis and therapy of intestinal diseases
Y Zhang, J Zhang, L Duan - Pharmacological research, 2022 - Elsevier
The interaction between mitochondria and gut microbiota plays a critical role in intestinal
physiological homeostasis. In this kind of homeostasis, intestinal epithelial hypoxia helps …
physiological homeostasis. In this kind of homeostasis, intestinal epithelial hypoxia helps …
Crosstalk between the gut microbiota and epithelial cells under physiological and infectious conditions
A Zhou, Y Yuan, M Yang, Y Huang, X Li, S Li… - Frontiers in Cellular …, 2022 - frontiersin.org
The gastrointestinal tract (GIT) is considered the largest immunological organ, with a diverse
gut microbiota, that contributes to combatting pathogens and maintaining human health …
gut microbiota, that contributes to combatting pathogens and maintaining human health …