Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics

C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

Trehalose in biomedical cryopreservation–properties, mechanisms, delivery methods, applications, benefits, and problems

Y Hu, X Liu, F Liu, J ** dimethyl sulfoxide (DMSO)-free cryopreservation protocols for biotherapeutics
MD Ekpo, GF Boafo, J **e, X Liu, C Chen… - Frontiers in …, 2022 - frontiersin.org
Cryopreservation is a technology employed in long-term storage of biologics achieved by
cooling to cryogenic temperatures (1, 2). This preservation technique has become …

Investigating the cryoprotective efficacy of fructans in mammalian cell systems via a structure-functional perspective

S Tornacı, M Erginer, B Gökalsın, A Aysan, M Çetin… - Carbohydrate …, 2024 - Elsevier
Fructans have long been known with their role in protecting organisms against various
stress factors due to their ability to induce controlled dehydration and support membrane …

Evaluation of heat transfer in porous scaffolds under cryogenic treatment: a numerical study

K Deshmukh, S Gupta, A Bit - Medical & Biological Engineering & …, 2023 - Springer
The present work had evaluated the effect of cryogenic treatment (233 K) on the degradation
of polymeric biomaterial using a numerical model. The study on effect of cryogenic …