[HTML][HTML] Subsequent Waves of Convergent Evolution in SARS-CoV-2 Genes and Proteins

D Focosi, PG Spezia, F Maggi - Vaccines, 2024 - mdpi.com
Beginning in 2022, following widespread infection and vaccination among the global
population, the SARS-CoV-2 virus mainly evolved to evade immunity derived from vaccines …

Deletion of V483 in the spike confers evolutionary advantage on SARS-CoV-2 for human adaptation and host-range expansion after a prolonged pandemic

C Yue, S Liu, B Meng, K Fan, S Yang, P Liu, Q Zhu… - Cell Research, 2024 - nature.com
Dear Editor, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
undergone continuous evolution since its initial outbreak in 2019. The emergence of …

Conserved role of spike S2 domain N-glycosylation across betacoronaviruses

Q Yang, A Kelkar, B Manicassamy, S Neelamegham - npj Viruses, 2025 - nature.com
Besides acting as an immunological shield, the N-glycans of SARS-CoV-2 are also critical
for viral life cycle. As the S2 subunit of spike is highly conserved across betacoronaviruses …

Conserved role of spike S2 domain N-glycosylation across beta-coronavirus family

Q Yang, A Kelkar, B Manicassamy, S Neelamegham - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Besides acting as an immunological shield, the N-glycans of SARS-CoV-2 are also critical
for viral life cycle. As the S2 subunit of spike is highly conserved across beta-coronaviruses …

The Glycobiology of SARS-CoV-2 Virus and Development of Virus-Like-Particles (VLPs) for mRNA Delivery

Q Yang - 2024 - search.proquest.com
The spike protein of SARS-CoV-2 virus is extensively glycosylated with 22 N-linked glycans
and potential O-linked glycans per monomer. To study the effects of these carbohydrate …