Damage to the central nervous system (CNS) results in a glial reaction, leading eventually to
the formation of a glial scar. In this environment, axon regeneration fails, and remyelination …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Matrix metalloproteinases (MMPs) regulate ductal morphogenesis, apoptosis, and
neoplastic progression in mammary epithelial cells. To elucidate the direct effects of MMPs …

Walker-Warburg syndrome (WWS) is an autosomal recessive developmental disorder
characterized by congenital muscular dystrophy and complex brain and eye abnormalities …

Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very
restricted pattern of expression but an enormously diverse range of functions. Here, we …

We have previously shown that aggregation of microbeads coated with N-CAM and Ng-CAM
is inhibited by incubation with soluble neurocan, a chondroitin sulfate proteoglycan of brain …

Research of the past 25 years has shown that astrocytes do more than participating and
building up the blood-brain barrier and detoxify the active synapse by reuptake of …

Injury to the adult mammalian CNS results in reactive changes among the glial cells
surrounding the site of damage. Recently, an unusual class of glial cells has been identified …

By combining both immunocytochemical and functional investigations, a hypothetical
framework will be developed for the molecular mechanisms underlying neuron-glia …

It is well established that axonal regeneration in the adult CNS is largely unsuccessful.
Numerous axon‐inhibitory molecules are now known to be present in the injured CNS, and …