Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …

OBJECTIVE: To illustrate the necessity for an enhanced understanding of the genetic basis
of male factor infertility, to present a comprehensive synopsis of these genetic elements, and …

Carcinoma in situ testis (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a
pre-invasive precursor of testicular germ cell tumours, the commonest cancer type of male …

Capsule This expert opinion summarizes current knowledge on risk factors for infertility and
identifies a practical clinical and diagnostic approach for the male and female partners of an …

This review paper highlights important diagnostic and therapeutic concerns for girls with
Complete Androgen Insensitivity Syndrome (CAIS). CAIS is an androgen receptor defect …

Intracytoplasmic sperm injection (ICSI) now provides fertility in many cases of severe
idiopathic spermatogenic failure and obstructive azoospermia. Genetic causes must be …

The subcellular distribution of steroidogenic enzymes has so far been studied mostly in
classical endocrine glands and in the placenta. In the peripheral intracrine organs which …

Although common reproductive problems, such as male infertility and testicular cancer,
present in adult life, strong evidence exists that these reproductive disorders might have a …

Many genetic polymorphisms have been studied extensively to elucidate their role in the
pathophysiology of male infertility. This article presents a review of the literature following a …

There are few systematic studies of the relationship between blood testosterone
concentrations and the symptoms of overt androgen deficiency. Because most testosterone …