The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …

Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Development of innovative nanomedicine formulations to traverse the blood–brain barrier
(BBB) for effective theranostics of glioma remains a great challenge. Herein, we report the …

Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …

The blood–brain barrier (BBB) exists between plasma and brain tissue. It comprises a
capillary wall and glial cells and prevents external substances, including therapeutic agents …

Ultrasound-responsive polymeric materials have received a tremendous amount of attention
from scientists for several decades. Compared to other stimuli-responsive materials (such as …

Glioblastoma multiforme is one of the most fatal intracranial tumors with no effective
treatment. The drug concentration in tumor sites is usually insufficient to reach therapeutic …

Glioma features high fatality rate and short survival time of patients due to its fast growth
speed and high invasiveness, hence timely treatment of early‐stage glioma is extremely …

The delivery of therapeutics to the brain in an efficient, noninvasive manner continues to be
a major unmet need in the field of drug delivery. One significant impediment to brain delivery …

Therapeutic options for neurological disorders currently remain limited. The intrinsic
complexity of the brain architecture prevents potential therapeutics from reaching their …