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Inflammation in traumatic brain injury
There is an increasing evidence that inflammation contributes to clinical and functional
outcomes in traumatic brain injury (TBI). Many successful target-engaging, lesion-reducing …
outcomes in traumatic brain injury (TBI). Many successful target-engaging, lesion-reducing …
The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: a status report
EH McNamara, AA Grillakis, LB Tucker… - Experimental neurology, 2020 - Elsevier
Closed-head traumatic brain injury (TBI) is a worldwide concern with increasing prevalence
and cost to society. Rotational acceleration is a primary mechanism in TBI that results from …
and cost to society. Rotational acceleration is a primary mechanism in TBI that results from …
Fixed time-point analysis reveals repetitive mild traumatic brain injury effects on resting state functional magnetic resonance imaging connectivity and neuro-spatial …
Repetitive mild traumatic brain injuries (rmTBIs) are serious trauma events responsible for
the development of numerous neurodegenerative disorders. A major challenge in …
the development of numerous neurodegenerative disorders. A major challenge in …
Repeated mild head injury leads to wide-ranging deficits in higher-order cognitive functions associated with the prefrontal cortex
Traumatic brain injury (TBI) has long been identified as a precipitating risk factor for higher-
order cognitive deficits associated with the frontal and prefrontal cortices (PFC). In addition …
order cognitive deficits associated with the frontal and prefrontal cortices (PFC). In addition …
Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal …
Background Appropriately modulating inflammation after traumatic brain injury (TBI) may
prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of …
prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of …
Acute blood levels of neurofilament light indicate one-year white matter pathology and functional impairment in repetitive mild traumatic brain injured mice
F Moro, I Lisi, D Tolomeo, G Vegliante… - Journal of …, 2023 - liebertpub.com
Mild traumatic brain injury (mTBI) mostly causes transient symptoms, but repeated (r) mTBI
can lead to neurodegenerative processes. Diagnostic tools to evaluate the presence of …
can lead to neurodegenerative processes. Diagnostic tools to evaluate the presence of …
Diffusion tensor imaging of the evolving response to mild traumatic brain injury in rats
Mild traumatic brain injury (mTBI), also known as concussion, is a serious public health
challenge. Although most patients recover, a substantial minority suffers chronic disability …
challenge. Although most patients recover, a substantial minority suffers chronic disability …
Altered tau kinase activity in rTg4510 mice after a single interfaced CHIMERA traumatic brain injury
Traumatic brain injury (TBI) is an established risk factor for neurodegenerative diseases. In
this study, we used the Closed Head Injury Model of Engineered Rotational Acceleration …
this study, we used the Closed Head Injury Model of Engineered Rotational Acceleration …
Juvenile mild traumatic brain injury elicits distinct spatiotemporal astrocyte responses
T Clément, JB Lee, A Ichkova, B Rodriguez‐Grande… - Glia, 2020 - Wiley Online Library
Mild‐traumatic brain injury (mTBI) represents~ 80% of all emergency room visits and
increases the probability of develo** long‐term cognitive disorders in children. To date …
increases the probability of develo** long‐term cognitive disorders in children. To date …
PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury
CH Acosta, GA Clemons, CT Citadin, WC Carr… - Experimental …, 2023 - Elsevier
Mild traumatic brain injury (TBI) comprises the largest percentage of TBI-related injuries, with
pathophysiological and functional deficits that persist in a subset of TBI patients. In our three …
pathophysiological and functional deficits that persist in a subset of TBI patients. In our three …