Physiology and neurobiology of stress and adaptation: central role of the brain
BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …
The neuro-symphony of stress
The impact of stress on brain function is increasingly recognized. Various substances are
released in response to stress and can influence distinct neuronal circuits, but the functional …
released in response to stress and can influence distinct neuronal circuits, but the functional …
The blood-testis barrier and its implications for male contraception
CY Cheng, DD Mruk, DR Sibley - Pharmacological reviews, 2012 - Elsevier
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …
When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
CL Raison, AH Miller - American Journal of Psychiatry, 2003 - Am Psychiatric Assoc
OBJECTIVE: Previous theories have emphasized the role of excessive glucocorticoid activity
in the pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling …
in the pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling …
Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
The glucocorticoid receptor: pivot of depression and of antidepressant treatment?
Hyperactivity of the hypothalamus–pituitary–adrenal (HPA) axis and increased levels of
glucocorticoid hormones in patients with depression have mostly been ascribed to impaired …
glucocorticoid hormones in patients with depression have mostly been ascribed to impaired …
Omega‐3 fatty acids and depression: scientific evidence and biological mechanisms
The changing of omega‐6/omega‐3 polyunsaturated fatty acids (PUFA) in the food supply of
Western societies occurred over the last 150 years is thought to promote the pathogenesis of …
Western societies occurred over the last 150 years is thought to promote the pathogenesis of …
Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
W Löscher, H Potschka - Progress in neurobiology, 2005 - Elsevier
The blood–brain barrier (BBB) serves as a protective mechanism for the brain by preventing
entry of potentially harmful substances from free access to the central nervous system …
entry of potentially harmful substances from free access to the central nervous system …
[HTML][HTML] The effects of magnesium supplementation on subjective anxiety and stress—a systematic review
Background: Anxiety related conditions are the most common affective disorders present in
the general population with a lifetime prevalence of over 15%. Magnesium (Mg) status is …
the general population with a lifetime prevalence of over 15%. Magnesium (Mg) status is …
Unraveling the time domains of corticosteroid hormone influences on brain activity: rapid, slow, and chronic modes
Brain cells are continuously exposed to corticosteroid hormones, although the levels vary
(eg, after stress). Corticosteroids alter neural activity via two receptor types …
(eg, after stress). Corticosteroids alter neural activity via two receptor types …