Vaginal infections such as bacterial vaginosis (BV), chlamydia, gonorrhea, genital herpes,
candidiasis, and trichomoniasis affect millions of women each year. They are caused by an …

The vagina is a promising site for both local and systemic drug delivery and represents an
interesting administration route for compounds with poor oral bioavailability. Whereas most …

The engineering of crystalline multi-component drug systems, including cocrystals and salts,
is now an established method of modifying the physicochemical properties and dissolution …

Over the past decades, comprehensive attempts have been made to improve physiological
absorption by designing delivery systems, using suitable carriers, and altering the route of …

We provide a simple, robust, and novel method based on a stable dispersion of α-alumina
(Al 2 O 3) nanoparticles to modified glassy carbon electrode (GCE) for the quantitative …

Highlights•Vaginal anatomy and evading the first-pass effect make the vagina the perfect
site for drug delivery.•Perks of novel VDDS are increased retention time and controlled …

The genitourinary syndrome of menopause (GSM) is a widely occurring condition affecting
millions of women worldwide. The current treatment of GSM involves the use of orally or …

Objective: Trichomoniasis is a common sexually-transmitted disease that is associated with
increased perinatal morbidity and human immunodeficiency virus (HIV) transmission. This …

Bioadhesive vaginal film is becoming a more effective and convenient dosage form
compared to suppositories and gel for vaginal application as a method for the treatment of …

Polycaprolactone (PCL) matrices incorporating lactoferrin as a natural macromolecular
microbicide, were prepared by rapidly cooling a suspension of lactoferrin particulates in PCL …