Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

Long Noncoding RNA UCA1 in Gastrointestinal Cancers: Molecular Regulatory Roles and Patterns, Mechanisms, and Interactions

S Ramli, MS Sim, RM Guad, SCB Gopinath… - Journal of …, 2021 - Wiley Online Library
The rising trend of gastrointestinal (GI) cancer has become a global burden due to its
aggressive nature and poor prognosis. Long noncoding RNAs (lncRNAs) have recently …

Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways

S Chirumbolo, G Bjørklund, R Lysiuk, A Vella… - International journal of …, 2018 - mdpi.com
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …

Comprehensive review on herbal medicine: emphasis on current therapy and role of phytoconstituents for cancer treatment

AN Sharma, HK Dewangan… - Chemistry & …, 2024 - Wiley Online Library
Introduction: Cancer poses a significant public health challenge in both developed and
develo** nations, with a rising global incidence of patients facing the threat of death due …

Potential therapeutic implication of herbal medicine in mitochondria-mediated oxidative stress-related liver diseases

MN Park, MA Rahman, MH Rahman, JW Kim, M Choi… - Antioxidants, 2022 - mdpi.com
Mitochondria are double-membrane organelles that play a role in ATP synthesis, calcium
homeostasis, oxidation-reduction status, apoptosis, and inflammation. Several human …

[HTML][HTML] Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

P Ramakrishnan, WM Loh, SCB Gopinath… - … Pharmaceutica Sinica B, 2020 - Elsevier
Activated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of
excessive pancreatic fibrosis, which is a crucial hallmark of chronic pancreatitis (CP) and its …

[HTML][HTML] Synthesis and Characterization of Chemically and Green-Synthesized Silver Oxide Particles for Evaluation of Antiviral and Anticancer Activity

M Asif, W Iqbal, M Fakhar-e-Alam, Z Hussain… - Pharmaceuticals, 2024 - mdpi.com
Silver oxide (Ag2O) particles are wonderful candidates due to their unique properties, and
their use in a wide range of research, industrial and biomedical applications is rapidly …

Immunometabolism modulation, a new trick of edible and medicinal plants in cancer treatment

W Tan, T Pan, S Wang, P Li, Y Men, R Tan, Z Zhong… - Food chemistry, 2022 - Elsevier
The edible and medicinal plants (EMPs) are becoming an abundant source for cancer
prevention and treatment since the natural and healthy trend for modern human beings …

[HTML][HTML] Chemistry, pharmacology and therapeutic potential of swertiamarin–A promising natural lead for new drug discovery and development

NSM Fadzil, M Sekar, SH Gan, SR Bonam… - Drug design …, 2021 - ncbi.nlm.nih.gov
Swertiamarin, a seco-iridoid glycoside, is mainly found in Enicostemma littorale Blume (E.
littorale) and exhibits therapeutic activities for various diseases. The present study aimed to …

[PDF][PDF] Deciphering Synsepalum dulcificum as an Arising Phytotherapy Agent: Background, Phytochemical and Pharmacological Properties with Associated Molecular …

JW Ee, A Velaga, RM Guad, V Subramaniyan… - Sains Malaysiana, 2022 - ukm.my
Medicinal plants with less side effects are paramount important for humankind to cure
various ailments as compared to newly developed allopathic medicines. Synsepalum …