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The genetic theory of adaptation: a brief history
HA Orr - Nature reviews genetics, 2005 - nature.com
Theoretical studies of adaptation have exploded over the past decade. This work has been
inspired by recent, surprising findings in the experimental study of adaptation. For example …
inspired by recent, surprising findings in the experimental study of adaptation. For example …
A comprehensive survey on fitness landscape analysis
In the past, the notion of fitness landscapes has found widespread adoption. Many different
methods have been developed that provide a general and abstract framework applicable to …
methods have been developed that provide a general and abstract framework applicable to …
[PDF][PDF] Fast folding and comparison of RNA secondary structures
Computer codes for computation and comparison of RNA secondary structures, the Vienna
RNA paCKage, are presented, that are based on dynamic programming algorithms and aim …
RNA paCKage, are presented, that are based on dynamic programming algorithms and aim …
Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
Comprehensive identification of all functional elements encoded in the human genome is a
fundamental need in biomedical research. Here, we present a comparative analysis of the …
fundamental need in biomedical research. Here, we present a comparative analysis of the …
From sequences to shapes and back: a case study in RNA secondary structures
RNA folding is viewed here as a map assigning secondary structures to sequences. At fixed
chain length the number of sequences far exceeds the number of structures. Frequencies of …
chain length the number of sequences far exceeds the number of structures. Frequencies of …
A survey of techniques for characterising fitness landscapes and some possible ways forward
Real-world optimisation problems are often very complex. Metaheuristics have been
successful in solving many of these problems, but the difficulty in choosing the best …
successful in solving many of these problems, but the difficulty in choosing the best …
[ספר][B] Introduction to artificial life
C Adami - 1998 - books.google.com
Developed from a lab-orientated multidisciplinary course, this book and CD-ROM package
brings together the theoretical groundwork for understanding the dynamics of systems of self …
brings together the theoretical groundwork for understanding the dynamics of systems of self …
Neutral evolution of mutational robustness
We introduce and analyze a general model of a population evolving over a network of
selectively neutral genotypes. We show that the population's limit distribution on the neutral …
selectively neutral genotypes. We show that the population's limit distribution on the neutral …
Biophysics of protein evolution and evolutionary protein biophysics
The study of molecular evolution at the level of protein-coding genes often entails comparing
large datasets of sequences to infer their evolutionary relationships. Despite the importance …
large datasets of sequences to infer their evolutionary relationships. Despite the importance …
Plasticity, evolvability, and modularity in RNA
RNA folding from sequences into secondary structures is a simple yet powerful,
biophysically grounded model of a genotype–phenotype map in which concepts like …
biophysically grounded model of a genotype–phenotype map in which concepts like …