Z-drugs, benzodiazepines and ketamine are classes of psychotropic drugs prescribed for
treating anxiety, sleep disorders and depression with known side effects including an …

Ashwagandha (Withania somnifera L. Dunal), an Indian medicinal plant that has been used
for centuries to treat insomnia, exhibits a variety of biological activities, such as improving …

Purpose We report a case of a polydrug user who consumed various synthetic cannabinoids
and fentanyl from a transdermal patch via a bucket bong. Toxicological results from …

Introduction As policies have been implemented to limit access to prescription opioids, other
drugs have been prescribed off-label, sometimes concurrently with opioids, to manage pain …

Background Previous studies demonstrate that the reformulation of OxyContin in the US in
2010 induced substitution to illicit opioids, causing illicit opioid markets to grow …

Background While the mandate to check patients' prescription history in Prescription Drug
Monitoring Program (PDMP) database before prescribing/dispensing controlled drugs has …

Population-level patterns in determinants of risky polysubstance use receive little attention
despite rising mortality. We use secondary data from the National Survey on Drug Use and …

Abstract Background and Aim Sedative, hypnotic or anxiolytic use disorders (SHA‐UD) are
defined by significant impairment or distress caused by recurrent sedative, hypnotic or …

Background: The role of prescribed opioids and benzodiazepines as risk factors for opioid
overdose are well established, however, their role as potential 'triggers' of opioid overdose …

Background Co-use of benzodiazepines and/or 'z-drugs' along with opioids is linked to the
rise in drug related deaths (DRD) in the UK. Understanding patterns of co-use could inform …