Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …
body and occur as a side effect of many reactions that take place in the human body. Under …
Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history
Ethnopharmacological relevance Cannabis sativa L.(C. sativa) is an annual dioecious plant,
which shares its origins with the inception of the first agricultural human societies in Asia …
which shares its origins with the inception of the first agricultural human societies in Asia …
Terpene derivatives as a potential agent against antimicrobial resistance (AMR) pathogens
The evolution of antimicrobial resistance (AMR) in pathogens has prompted extensive
research to find alternative therapeutics. Plants rich with natural secondary metabolites are …
research to find alternative therapeutics. Plants rich with natural secondary metabolites are …
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats
Q Hu, T Zuo, L Deng, S Chen, W Yu, S Liu, JD Liu… - Phytomedicine, 2022 - Elsevier
Background Ischemic stroke is a complex brain disease regulated by several cell death
processes, including apoptosis, autophagy, and ferroptosis. β-Caryophyllene (BCP), a …
processes, including apoptosis, autophagy, and ferroptosis. β-Caryophyllene (BCP), a …
Fibromyalgia: recent advances in diagnosis, classification, pharmacotherapy and alternative remedies
ME Maffei - International journal of molecular sciences, 2020 - mdpi.com
Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic
disease. FM is a condition which has been associated with diseases such as infections …
disease. FM is a condition which has been associated with diseases such as infections …
Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis
AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …
the endocannabinoid system have received an increasing amount of interest related to their …
A review on the traditional uses, phytochemistry, and pharmacological activities of clove basil (Ocimum gratissimum L.)
In traditional medicine, Ocimum gratissimum (clove basil) is used in the treatment of various
diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and …
diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and …
Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus
T Nuutinen - European journal of medicinal chemistry, 2018 - Elsevier
Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes–both
are typically comprised of terpenes as up to 3–5% of the dry-mass of the female …
are typically comprised of terpenes as up to 3–5% of the dry-mass of the female …
Cannabis pharmacology: the usual suspects and a few promising leads
EB Russo, J Marcu - Advances in pharmacology, 2017 - Elsevier
The golden age of cannabis pharmacology began in the 1960s as Raphael Mechoulam and
his colleagues in Israel isolated and synthesized cannabidiol, tetrahydrocannabinol, and …
his colleagues in Israel isolated and synthesized cannabidiol, tetrahydrocannabinol, and …
β-Caryophyllene: a sesquiterpene with countless biological properties
F Francomano, A Caruso, A Barbarossa, A Fazio… - Applied sciences, 2019 - mdpi.com
β-Caryophyllene (BCP), a natural bicyclic sesquiterpene, is a selective phytocannabinoid
agonist of type 2 receptors (CB2-R). It isn't psychogenic due to the absence of an affinity to …
agonist of type 2 receptors (CB2-R). It isn't psychogenic due to the absence of an affinity to …