Recent liquid chromatographic approaches and developments for the separation and purification of carbohydrates

G Nagy, T Peng, NLB Pohl - Analytical Methods, 2017 - pubs.rsc.org
Carbohydrate purification remains a bottleneck in securing analytical standards from natural
sources or by chemical or enzymatic synthesis. This review highlights the scope and …

Lactose-functionalized carbosilane glycodendrimers are highly potent multivalent ligands for galectin-9 binding: increased glycan affinity to galectins correlates with …

M Müllerová, M Hovorková, T Závodná… - …, 2023 - ACS Publications
Galectins, the glycan binding proteins, and their respective carbohydrate ligands represent a
unique fundamental regulatory network modulating a plethora of biological processes. The …

From d- to l-Monosaccharide Derivatives via Photodecarboxylation–Alkylation

ICS Wan, MD Witte, AJ Minnaard - Organic letters, 2019 - ACS Publications
Photodecarboxylation–alkylation of conformationally locked monosaccharides leads to
inversion of stereochemistry at C5. This allows the synthesis of l-sugars from their readily …

Biosynthesis and biological activity of carbasugars

S Roscales, J Plumet - International Journal of Carbohydrate …, 2016 - Wiley Online Library
The first synthesis of carbasugars, compounds in which the ring oxygen of a
monosaccharide had been replaced by a methylene moiety, was described in 1966 by …

Synthesis of Multivalent Carbohydrate‐Centered Glycoclusters as Nanomolar Ligands of the Bacterial Lectin LecA from Pseudomonas aeruginosa

ML Gening, DV Titov, S Cecioni… - … A European Journal, 2013 - Wiley Online Library
A family of fifteen glycoclusters based on a cyclic oligo‐(1→ 6)‐β‐d‐glucosamine core has
been designed as potential inhibitors of the bacterial lectin LecA with various valencies …

Carbosilane glycodendrimers for anticancer drug delivery: synthetic route, characterization, and biological effect of Glycodendrimer–Doxorubicin complexes

M Mullerova, D Maciel, N Nunes, D Wrobel… - …, 2021 - ACS Publications
The complexity of drug delivery mechanisms calls for the development of new transport
system designs. Here, we report a robust synthetic procedure toward stable glycodendrimer …

[HTML][HTML] Removal of benzylidene acetal and benzyl ether in carbohydrate derivatives using triethylsilane and Pd/C

A Santra, T Ghosh, AK Misra - Beilstein Journal of Organic …, 2013 - beilstein-journals.org
Clean deprotection of carbohydrate derivatives containing benzylidene acetals and benzyl
ethers was achieved under catalytic transfer hydrogenation conditions by using a …

Protocol for the purification of protected carbohydrates: toward coupling automated synthesis to alternate-pump recycling high-performance liquid chromatography

EK Daniel, LB Nicola - Chemical Communications, 2016 - pubs.rsc.org
Given recent advances in automated oligosaccharide synthesis, analytical techniques that
can be coupled to a synthetic framework are needed to not just identify but also purify to …

[書籍][B] Reaction green metrics: problems, exercises, and solutions

J Andraos - 2018 - books.google.com
This book contains a series of exercises and problems posed in the subject of green metrics.
Essentially it is a" how to" book on evaluating the material efficiency, environmental impact …

Bioorthogonal metal-free click-ligation of c RGD-pentapeptide to alginate

A Krause, A Kirschning, G Draeger - Organic & Biomolecular …, 2012 - pubs.rsc.org
“Click” reactions have become very common and powerful ligation techniques, of which 1, 3-
dipolar cycloadditions have most frequently been employed. Since metal-mediated …