The maxillofacial skeleton is highly dynamic and requires a constant equilibrium between
the bone resorption and bone formation. The field of osteoimmunology explores the …

The development, establishment and repair of apical periodontitis (AP) is dependent of
several factors, which include host susceptibility, microbial infection, immune response …

Apical periodontitis is an inflammatory response caused by pulp infection. It induces bone
resorption in the apical and periapical regions of the tooth. The most conservative approach …

Introduction Apical periodontitis (AP) is a common consequence of root canal infection
leading to periapical bone resorption. Microbial and host genetic factors and their …

Pulpal and periapical diseases affect a large segment of the population. The role of
microbial infections and host effector molecules in these diseases is well established …

Objective To detect the distribution and expression levels of the nucleotide-binding
oligomerization domain-like receptor protein 3 (NLRP3) and the absent in Melanoma 2 …

Introduction The outcome of root canal treatment has been reported as intimately related to
the host response. Genetic polymorphisms might be associated with apical periodontitis …

Various disease-related genes have recently been identified using single nucleotide
polymorphisms (SNPs). This study identified disease-related genes by analyzing SNP using …

Aim To investigate the possible association between TNFα (− 308 G/A) and IL‐1β (− 511
C/T) single nucleotide polymorphisms (SNPs) and GSTT and GSTM deletion polymorphisms …

Estrogen plays critical roles in apical periodontitis and subsequent bone loss, however the
mechanism is not clear yet. In this study, we aimed to study the underlying mechanism of …