Drug repurposing to overcome microbial resistance
J Jampilek - Drug Discovery Today, 2022 - Elsevier
Infections are a growing global threat, and the number of resistant species of microbial
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
Anticancer applications of essential oils formulated into lipid-based delivery nanosystems
J Jampilek, K Kralova - Pharmaceutics, 2022 - mdpi.com
The use of natural compounds is becoming increasingly popular among patients, and there
is a renewed interest among scientists in nature-based bioactive agents. Traditionally …
is a renewed interest among scientists in nature-based bioactive agents. Traditionally …
Plant natural products for human health
The aim of this Special Issue on “Plant Natural Products for Human Health” is to compile a
series of scientific reports to demonstrate the medicinal potential of plant natural products …
series of scientific reports to demonstrate the medicinal potential of plant natural products …
Novel cannabidiol− carbamate hybrids as selective BuChE inhibitors: Docking-based fragment reassembly for the development of potential therapeutic agents against …
X Jiang, Z Zhang, J Zuo, C Wu, L Zha, Y Xu… - European journal of …, 2021 - Elsevier
Cannabidiol (CBD) and rivastigmine have been launched as drugs for treating dementia
and cholinesterases (ChEs) are ideal drug targets. This study focused on develo** novel …
and cholinesterases (ChEs) are ideal drug targets. This study focused on develo** novel …
Advances in nanostructures for antimicrobial therapy
J Jampilek, K Kralova - Materials, 2022 - mdpi.com
Microbial infections caused by a variety of drug-resistant microorganisms are more common,
but there are fewer and fewer approved new antimicrobial chemotherapeutics for systemic …
but there are fewer and fewer approved new antimicrobial chemotherapeutics for systemic …
Novel avenues for identification of new antifungal drugs and current challenges
J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
Tris (hydroxymethyl) methyl ammonium salts of biologically active carboxylic acids. Synthesis, properties and crystal structure
YA Kondratenko, AA Nikonorova, AA Zolotarev… - Journal of Molecular …, 2020 - Elsevier
Tris (hydroxymethyl) methyl ammonium salts,[C (CH 2 OH) 3 NH 3] X, were obtained for the
first time by the interaction of tris (hydroxymethyl) aminomethane (TRIS) with carboxylic …
first time by the interaction of tris (hydroxymethyl) aminomethane (TRIS) with carboxylic …
Substitution effects on the photophysical and photoredox properties of tetraaza [7] helicenes
J Rocker, JA Dresel, LA Krieger… - … A European Journal, 2023 - Wiley Online Library
A series of substituted derivatives of tetraaza [7] helicenes were synthesized and the
influence of the substitution on their photophysical and photoredox‐catalytic properties was …
influence of the substitution on their photophysical and photoredox‐catalytic properties was …
Study of Biological Activities and ADMET-Related Properties of Novel Chlorinated N-arylcinnamamides
T Strharsky, D Pindjakova, J Kos, L Vrablova… - International Journal of …, 2022 - mdpi.com
A series of eighteen 4-chlorocinnamanilides and eighteen 3, 4-dichlorocinnamanilides were
designed, prepared and characterized. All compounds were evaluated for their activity …
designed, prepared and characterized. All compounds were evaluated for their activity …
Novel benzene-based carbamates for AChE/BChE inhibition: Synthesis and ligand/structure-oriented SAR study
A series of new benzene-based derivatives was designed, synthesized and
comprehensively characterized. All of the tested compounds were evaluated for their in vitro …
comprehensively characterized. All of the tested compounds were evaluated for their in vitro …