Gap junctions form the cell-to-cell pathways for propagation of the precisely orchestrated
patterns of current flow that govern the regular rhythm of the healthy heart. As in most tissues …

Connexins, the protein molecules forming gap junction channels, are reduced in number or
redistributed from intercalated disks to lateral cell borders in a variety of cardiac diseases …

MicroRNAs (miRNAs) are a class of small noncoding RNAs that have gained status as
important regulators of gene expression. Here, we investigated the function and molecular …

Objectives: To describe the characteristics, treatment, and outcomes of active infective
endocarditis (IE) in Europe. Design: Prospective survey of medical practices in Europe …

Objective: We tested the hypothesis that structural remodeling of cellular connections,
alterations in the expression of connexins (Cx), and an increase in fibrosis represent …

Sudden cardiac death (SCD) is devastating at any age, but even more so when the
individual affected is young and asymptomatic, and the death is entirely unexpected. SCD is …

Regulation of gap junction (GJ) organization is critical for proper function of excitable tissues
such as heart and brain, yet mechanisms that govern the dynamic patterning of GJs remain …

Rationale: The early description of the intercalated disc defined 3 structures, all of them
involved in cell-cell communication: desmosomes, gap junctions, and adherens junctions …

Congestive heart failure is associated with a high risk of life-threatening ventricular re-
entrant arrhythmias. Down-regulation of the principal gap-junctional protein of the ventricular …

Gap junctions, assembled from connexins, form the cell-to-cell pathways for propagation of
the precisely orchestrated patterns of current flow that govern the regular rhythm of the …