Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

It is well established that multifactorial drug resistance hinders successful cancer treatment.
Tumor cell interactions with the tumor microenvironment (TME) are crucial in epithelial …

Anti-angiogenic therapy is one of the promising strategies for many types of solid cancers.
Bevacizumab (Avastin), a recombinant humanized monoclonal antibody of vascular …

Trophoblasts are important parts of the placenta and exert vital roles in the maternal‐foetal
crosstalk, and sufficient trophoblasts migration and invasion is critical for embryo …

Background The gut microbiome plays an important role in human health and disease.
Gnotobiotic animal and in vitro cell-based models provide some informative insights into …

Macrophages have a central role in numerous physiological processes, such as immune
defense, maintenance of tissue homeostasis, wound healing, and inflammation. Moreover …

In the last decade, cancer immunotherapies have produced impressive therapeutic results.
However, the potency of immunotherapy is tightly linked to immune cell infiltration within the …

Neutrophils are implicated in almost every stage of oncogenesis and paradoxically display
anti-and pro-tumor properties. Accumulating evidence indicates that neutrophils display …

A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate
inflammatory response that leads to immunopathological events. Cytokine storms can occur …

Tumor-associated macrophages (TAMs) have been implicated in the promotion of breast
cancer growth and metastasis, and a strong infiltration by TAMs has been associated with …