Molecular hydrogen reduces acute exercise-induced inflammatory and oxidative stress status

JE Nogueira, P Passaglia, CMD Mota… - Free Radical Biology …, 2018 - Elsevier
Physical exercise induces inflammatory and oxidative markers production in the skeletal
muscle and this process is under the control of both endogenous and exogenous …

Molecular hydrogen is a potential protective agent in the management of acute lung injury

Y Zhang, J Zhang, Z Fu - Molecular Medicine, 2022 - Springer
Acute lung injury (ALI) and acute respiratory distress syndrome, which is a more severe form
of ALI, are life-threatening clinical syndromes observed in critically ill patients. Treatment …

Intratumoral high-payload delivery and acid-responsive release of H2 for efficient cancer therapy using the ammonia borane-loaded mesoporous silica nanomedicine

T Yang, Z **, Z Wang, P Zhao, B Zhao, M Fan… - Applied Materials …, 2018 - Elsevier
Hydrogen gas therapy as an emerging and promising therapy strategy has overwhelming
advantages especially in bio-safety compared with other gas therapy routes, but is facing a …

Molecular hydrogen downregulates acute exhaustive exercise-induced skeletal muscle damage

JE Nogueira, MR Amorim, AP Pinto… - Canadian journal of …, 2021 - cdnsciencepub.com
Physical exercise-induced skeletal muscle damage may be characterized by increased
oxidative stress, inflammation, and apoptosis which may be beneficial when exercise is …

Mitochondrial function in lungs of rats with different susceptibilities to hyperoxia-induced Acute Lung Injury

P Taheri, DD Dave, RK Dash… - Journal of Applied …, 2024 - journals.physiology.org
Adult rats exposed to hyperoxia (> 95% O2) die from respiratory failure in 60–72 h. However,
rats preconditioned with> 95% O2 for 48 h followed by 24 h in room air acquire tolerance of …

Development of duramycin-based molecular probes for cell death imaging

D Zhang, M Gao, Q **, Y Ni, H Li, C Jiang… - Molecular Imaging and …, 2022 - Springer
Cell death is involved in numerous pathological conditions such as cardiovascular
disorders, ischemic stroke and organ transplant rejection, and plays a critical role in the …

Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records

P Luo, Y Ding, Y He, D Chen, Q He, Z Huang, S Huang… - Medicine, 2022 - journals.lww.com
A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19)
leads to considerable morbidity and mortality, which bring great challenge to respiratory …

Quantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G

SH Audi, A Cammarata, AV Clough… - Journal of Applied …, 2020 - journals.physiology.org
Mitochondrial membrane potential (Δψm) plays a key role in vital mitochondrial functions,
and its dissipation is a hallmark of mitochondrial dysfunction. The objective of this study was …

Multifaceted Immunomodulatory Nanocomplexes Target Neutrophilic‐ROS Inflammation in Acute Lung Injury

F Su, C Zhang, Q Zhang, Y Shen, S Li, J Shi… - Advanced …, 2024 - Wiley Online Library
The sepsis‐induced acute lung injury (ALI) still represents one of the leading causes of
death in critically ill patients, underscoring the need for novel therapies. Excessive activation …

Assessment of protection offered by the NRF2 pathway against hyperoxia-induced acute lung injury in NRF2 knockout rats

SH Audi, ER Jacobs, P Taheri, S Ganesh, AV Clough - Shock, 2022 - journals.lww.com
Nuclear factor erythroid 2-related factor (Nrf2) is a redox-sensitive transcription factor that
responds to oxidative stress by activating expressions of key antioxidant and cytoprotective …