aRNAque: an evolutionary algorithm for inverse pseudoknotted RNA folding inspired by Lévy flights
NSC Merleau, M Smerlak - BMC bioinformatics, 2022 - Springer
Background We study in this work the inverse folding problem for RNA, which is the
discovery of sequences that fold into given target secondary structures. Results We …
discovery of sequences that fold into given target secondary structures. Results We …
Principal component analysis characterizes shared pathogenetics from genome-wide association studies
D Chang, A Keinan - PLoS computational biology, 2014 - journals.plos.org
Genome-wide association studies (GWASs) have recently revealed many genetic
associations that are shared between different diseases. We propose a method, disPCA, for …
associations that are shared between different diseases. We propose a method, disPCA, for …
Ensemble Models Using Symbolic Regression and Genetic Programming for Uncertainty Estimation in ESG and Alternative Investments
P Venegas, I Britez, F Gobet - Big Data in Finance: Opportunities and …, 2022 - Springer
Trustable models exploit the diversity of model forms developed using symbolic regression
via genetic programming to define ensemble models. These models have been shown …
via genetic programming to define ensemble models. These models have been shown …
An integrated network approach to identifying biological pathways and environmental exposure interactions in complex diseases
Complex diseases are the result of intricate interactions between genetic, epigenetic and
environmental factors. In previous studies, we used epidemiological and genetic data linking …
environmental factors. In previous studies, we used epidemiological and genetic data linking …
Evolutionarily derived networks to inform disease pathways
BE Graham, C Darabos, M Huang… - Genetic …, 2017 - Wiley Online Library
Methods to identify genes or pathways associated with complex diseases are often
inadequate to elucidate most risk because they make implicit and oversimplified …
inadequate to elucidate most risk because they make implicit and oversimplified …
[LIVRE][B] Exploring the genetic architecture of complex diseases with genome-wide association studies
D Chang - 2014 - search.proquest.com
Over the past decade, the number of genome-wide association studies (GWAS) carried out
has increased exponentially. These studies, mostly by investigating single nucleotide …
has increased exponentially. These studies, mostly by investigating single nucleotide …