Transposable elements in Drosophila

V Mérel, M Boulesteix, M Fablet, C Vieira - Mobile DNA, 2020 - Springer
Drosophila has been studied as a biological model for many years and many discoveries in
biology rely on this species. Research on transposable elements (TEs) is not an exception …

Enforcement is central to the evolution of cooperation

JA Ågren, NG Davies, KR Foster - Nature Ecology & Evolution, 2019 - nature.com
Cooperation occurs at all levels of life, from genomes, complex cells and multicellular
organisms to societies and mutualisms between species. A major question for evolutionary …

Impact of microRNA regulation on variation in human gene expression

J Lu, AG Clark - Genome research, 2012 - genome.cshlp.org
MicroRNAs (miRNAs) are endogenously expressed small RNAs that regulate expression of
mRNAs at the post-transcriptional level. The consequence of miRNA regulation is …

A brief history of the status of transposable elements: from junk DNA to major players in evolution

C Biémont - Genetics, 2010 - academic.oup.com
The idea that some genetic factors are able to move around chromosomes emerged more
than 60 years ago when Barbara McClintock first suggested that such elements existed and …

Detection of circulating tumor cells in peripheral blood from patients with gastric cancer using piRNAs as markers

L Cui, Y Lou, X Zhang, H Zhou, H Deng, H Song… - Clinical …, 2011 - Elsevier
OBJECTIVE: To investigate the feasibility of detecting circulating cancer cells in peripheral
blood from gastric cancer patients using Piwi-interacting RNAs (piRNAs) as markers …

The origin of RNA interference: Adaptive or neutral evolution?

A Torri, J Jaeger, T Pradeu, MC Saleh - PLoS Biology, 2022 - journals.plos.org
The origin of RNA interference (RNAi) is usually explained by a defense-based hypothesis,
in which RNAi evolved as a defense against transposable elements (TEs) and RNA viruses …

TEtools facilitates big data expression analysis of transposable elements and reveals an antagonism between their activity and that of piRNA genes

E Lerat, M Fablet, L Modolo… - Nucleic acids …, 2017 - academic.oup.com
Over recent decades, substantial efforts have been made to understand the interactions
between host genomes and transposable elements (TEs). The impact of TEs on the …

Selfish genetic elements

JA Ågren, AG Clark - PLoS genetics, 2018 - journals.plos.org
Selfish genetic elements (historically also referred to as selfish genes, ultra-selfish genes,
selfish DNA, parasitic DNA, genomic outlaws) are genetic segments that can enhance their …

A combined miRNA–piRNA signature to detect Alzheimer's disease

G Jain, A Stuendl, P Rao, T Berulava… - Translational …, 2019 - nature.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing huge
emotional and economic burden to our societies. An effective therapy has not been …

Population Genomics of Transposable Elements in Drosophila melanogaster

DA Petrov, AS Fiston-Lavier, M Lipatov… - Molecular biology …, 2011 - academic.oup.com
Transposable elements (TEs) are the primary contributors to the genome bulk in many
organisms and are major players in genome evolution. A clear and thorough understanding …