Each antibody-producing B cell makes antibodies of unique specificity, reflecting a series of
ordered gene rearrangements which must be successfully performed if the cell is to survive …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Only mature B lymphocytes can enter the lymphoid follicles of spleen and lymph nodes and
thus efficiently participate in the immune response. Mature, long-lived B lymphocytes derive …

A subset of blood cells from patients with B-cell chronic lymphocytic leukemia (CLL)
spontaneously differentiates in vitro into large, round, or fibroblast-like adherent cells that …

THE tyrosine kinase Syk (relative molecular mass 72,000), which is widely expressed in
haematopoietic cells, becomes associated with and activated by engagement of the B-cell …

BLyS and APRIL have similar but distinct biological roles, mediated through two known TNF
receptor family members, TACI and BCMA. We show that mice treated with TACI-Ig and …

Marrow stromal cells (MSCs) provide important survival and drug resistance signals to
chronic lymphocytic leukemia (CLL) cells, but current models to analyze CLL–MSC …

The lymphoid tissue of Waldeyer's ring, and particularly the nasopharyngeal tonsil
(adenoids), appears to be functionally comparable to nasal-associated lymphoid tissue in …

To analyze the immunoglobulin repertoire of human IgM+ B cells and the CD5 (+) and CD5 (-
) subsets, individual CD19 (+)/IgM+/CD5 (+) or CD5 (-) B cells were sorted and non …