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PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
Plant microRNAs: biogenesis, homeostasis, and degradation
J Wang, J Mei, G Ren - Frontiers in plant science, 2019 - frontiersin.org
MicroRNAs (miRNAs), a class of endogenous, tiny, non-coding RNAs, are master regulators
of gene expression among most eukaryotes. Intracellular miRNA abundance is regulated …
of gene expression among most eukaryotes. Intracellular miRNA abundance is regulated …
Regulation of microRNA biogenesis
M Ha, VN Kim - Nature reviews Molecular cell biology, 2014 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
One loop to rule them all: the **-pong cycle and piRNA-guided silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …
the genetic information of animal germ cells from the deleterious effects of molecular …
Diversifying microRNA sequence and function
MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …
now beginning to understand how they are generated, assembled into functional complexes …
[HTML][HTML] The long and short of microRNA
MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In
order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is …
order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is …
Time-resolved small RNA sequencing unravels the molecular principles of microRNA homeostasis
Argonaute-bound microRNAs silence mRNA expression in a dynamic and regulated
manner to control organismal development, physiology, and disease. We employed …
manner to control organismal development, physiology, and disease. We employed …
The MicroRNA family gets wider: the IsomiRs classification and role
MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding RNAs and are
engaged in many cellular processes, including cell differentiation, development, and …
engaged in many cellular processes, including cell differentiation, development, and …
IsomiRs–the overlooked repertoire in the dynamic microRNAome
The development of deep sequencing has enabled the identification of novel microRNAs
(miRNAs), leading to a growing appreciation for the fact that individual miRNAs can be …
(miRNAs), leading to a growing appreciation for the fact that individual miRNAs can be …
A single mechanism of biogenesis, initiated and directed by PIWI proteins, explains piRNA production in most animals
In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
regulate gene expression. The mechanisms for making piRNAs have been proposed to …