Immune checkpoint inhibitor-associated pneumonitis in non-small cell lung cancer: current understanding in characteristics, diagnosis, and management

Q Zhang, L Tang, Y Zhou, W He, W Li - Frontiers in immunology, 2021 - frontiersin.org
Immunotherapy that includes programmed cell death-1 (PD-1), programmed cell death-
ligand 1 (PD-L1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibitors has …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

J Haanen, M Obeid, L Spain, F Carbonnel… - Annals of …, 2022 - annalsofoncology.org
Adverse events (AEs) related to the use of immune checkpoint inhibitor (ICI) therapy are
defined as immune-related (IR) AEs (irAEs). irAEs are graded according to the Common …

[HTML][HTML] Corticosteroid-resistant immune-related adverse events: a systematic review

E Daetwyler, T Wallrabenstein, D König… - … for immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Immune checkpoint inhibitor (ICI) treatment has become an important therapeutic option for
various cancer types. Although the treatment is effective, ICI can overstimulate the patient's …

[HTML][HTML] Steroid-refractory PD-(L) 1 pneumonitis: incidence, clinical features, treatment, and outcomes

A Balaji, M Hsu, CT Lin, J Feliciano… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Immune-checkpoint inhibitor (ICI)-pneumonitis that does not improve or resolve
with corticosteroids and requires additional immunosuppression is termed steroid-refractory …

[HTML][HTML] Success and failure of additional immune modulators in steroid-refractory/resistant pneumonitis related to immune checkpoint blockade

J Beattie, H Rizvi, P Fuentes, J Luo… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Pneumonitis related to immune checkpoint blockade is uncommon but can be
severe, fatal or chronic. Steroids are first-line treatment, however, some patients are …

Pulmonary toxicities associated with the use of immune checkpoint inhibitors: An update from the immuno-oncology subgroup of the neutropenia, infection & …

BL Rapoport, VR Shannon, T Cooksley… - Frontiers in …, 2021 - frontiersin.org
The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer
treatment, with agents such as nivolumab, pembrolizumab, and cemiplimab targeting …

Checkpoint inhibitor pneumonitis: mechanisms, characteristics, management strategies, and beyond

JE Reuss, K Suresh, J Naidoo - Current oncology reports, 2020 - Springer
Abstract Purpose of Review Checkpoint inhibitor pneumonitis (CIP) is a toxicity of immune
checkpoint blockade (ICB) that can be highly morbid and at times fatal. Here, we review the …

Insights into potential pathogenesis and treatment options for immune-checkpoint inhibitor-related pneumonitis

H Ando, K Suzuki, T Yanagihara - Biomedicines, 2021 - mdpi.com
Immune-checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4),
programmed cell death-1 (PD-1), and programmed cell death-1-ligand 1 (PD-L1) have …

Tofacitinib for treatment in immune-mediated myocarditis: The first reported cases

Y Liu, L Jiang - Journal of Oncology Pharmacy Practice, 2021 - journals.sagepub.com
Introduction Immune checkpoint inhibitors (ICI) has demonstrated significant clinical benefit
in advanced cancer. Despite favorable benefits, the use of ICI is accompanied by various …