Polymeric scaffolds in tissue engineering: a literature review

M Jafari, Z Paknejad, MR Rad… - … Research Part B …, 2017 - Wiley Online Library
The tissue engineering scaffold acts as an extracellular matrix that interacts to the cells prior
to forming new tissues. The chemical and structural characteristics of scaffolds are major …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Limbal stem cell deficiency: current treatment options and emerging therapies

M Haagdorens, SI Van Acker… - Stem cells …, 2016 - Wiley Online Library
Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition
leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular …

Regenerative medicine and drug delivery: Progress via electrospun biomaterials

M Doostmohammadi, H Forootanfar… - Materials Science and …, 2020 - Elsevier
Worldwide research on electrospinning enabled it as a versatile technique for producing
nanofibers with specified physio-chemical characteristics suitable for diverse biomedical …

[HTML][HTML] Characterization of extracellular matrix modified poly (ε-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration

J Fernández-Pérez, KE Kador, AP Lynch… - Materials Science and …, 2020 - Elsevier
Alternatives to donor cornea transplantation based on tissue engineering are desirable to
overcome the current severe donor tissue shortage. Many natural polymers have good …

Use of polycaprolactone in corneal tissue engineering: A review

AOM Salehi, SH Keshel, F Sefat, L Tayebi - Materials Today …, 2021 - Elsevier
Corneal transplantation has been applied mainly for common corneal diseases. Although it
has been used formerly as a common treatment, it suffers some shortcomings such as the …

Biologicals and biomaterials for corneal regeneration and vision restoration in limbal stem cell deficiency

N Di Girolamo - Advanced Materials, 2024 - Wiley Online Library
The mammalian cornea is decorated with stem cells bestowed with the life‐long task of
renewing the epithelium, provided they remain healthy, functional, and in sufficient numbers …

Recent advancements in polymeric nanofibers for ophthalmic drug delivery and ophthalmic tissue engineering

D Sakpal, S Gharat, M Momin - Biomaterials Advances, 2022 - Elsevier
Nanofibers due to their unique properties such as high surface-to-volume ratio, porous
structure, mechanical strength, flexibility and their resemblance to the extracellular matrix …

Electrospun scaffolds for corneal tissue engineering: A review

B Kong, S Mi - Materials, 2016 - mdpi.com
Corneal diseases constitute the second leading cause of vision loss and affect more than 10
million people globally. As there is a severe shortage of fresh donated corneas and an …

Electrospun nanofibers for manipulating soft tissue regeneration

X Zhang, Y Meng, B Gong, T Wang, Y Lu… - Journal of Materials …, 2022 - pubs.rsc.org
Soft tissue damage is a common clinical problem that affects the lives of a large number of
patients all over the world. It is of great importance to develop functional scaffolds to …