Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …
An insular view of anxiety
We propose a general hypothesis that integrates affective and cognitive processing with
neuroanatomy to explain anxiety pronenes. The premise is that individuals who are prone to …
neuroanatomy to explain anxiety pronenes. The premise is that individuals who are prone to …
A fronto–striato–subthalamic–pallidal network for goal-directed and habitual inhibition
Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …
and goal-directed behaviours. In this article, we review recent evidence that expands this …
Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder
BACKGROUND: Neuroimaging studies have shown that major depressive disorder (MDD)
is accompanied by structural and functional abnormalities in specific brain regions and …
is accompanied by structural and functional abnormalities in specific brain regions and …
Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Obsessive-compulsive disorder (OCD) affects approximately 2–3% of the population and is
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
A multidimensional model of obsessive-compulsive disorder
D Mataix-Cols… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: Obsessive-compulsive disorder (OCD) is a clinically heterogeneous condition.
This heterogeneity can reduce the power and obscure the findings from natural history …
This heterogeneity can reduce the power and obscure the findings from natural history …
Midcingulate cortex: structure, connections, homologies, functions and diseases
BA Vogt - Journal of chemical neuroanatomy, 2016 - Elsevier
Midcingulate cortex (MCC) has risen in prominence as human imaging identifies unique
structural and functional activity therein and this is the first review of its structure …
structural and functional activity therein and this is the first review of its structure …
The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers
SR Chamberlain, AD Blackwell, NA Fineberg… - Neuroscience & …, 2005 - Elsevier
Obsessive compulsive disorder (OCD) is a highly debilitating neuropsychiatric condition with
estimated lifetime prevalence of 2–3%, more than twice that of schizophrenia. However, in …
estimated lifetime prevalence of 2–3%, more than twice that of schizophrenia. However, in …
[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …