Synthesis, biological activity and POM/DFT/docking analyses of annulated pyrano [2, 3-d] pyrimidine derivatives: Identification of antibacterial and antitumor …
Abstract New annulated pyrano [2, 3-d] pyrimidine derivatives were synthesized with
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
New tetrahydropyrimidine-1, 2, 3-triazole clubbed compounds: Antitubercular activity and Thymidine Monophosphate Kinase (TMPKmt) inhibition
Two series of new tetrahydropyrimidine (THPM)-1, 2, 3-triazole clubbed compounds were
designed, synthesized and screened for their antitubercular (anti-TB) activity against M …
designed, synthesized and screened for their antitubercular (anti-TB) activity against M …
Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis
In this study, new benzothiazole–pyrimidine hybrids (5a–c, 6, 7a–f, and 8–15) were
designed and synthesised. Two different functionalities on the pyrimidine moiety of lead …
designed and synthesised. Two different functionalities on the pyrimidine moiety of lead …
Synthesis of new pyrimidine derivatives and their antiproliferative activity against selected human cancer cell lines
SM Awad, OA Fathalla, J Wietrzyk, M Milczarek… - Research on Chemical …, 2015 - Springer
Amino-2-thiouracil (1) was condensed with benzenesulfonyl chloride and p-toluenesulfonyl
chloride in presence of pyridine as an acid binder to give sulfonamides 2a, b, which could …
chloride in presence of pyridine as an acid binder to give sulfonamides 2a, b, which could …
[PDF][PDF] Mg (OMe) 2 as a versatile catalyst for one-pot synthesis of 6-aryl-5-cyano-2-(oxo/thio) uracil derivatives and their antimicrobial evaluations
YLN Murthy, RMR Saviri, AR Parimi… - Organic …, 2013 - acgpubs.org
A series of substituted 6-aryl 5-cyano 2-uracil and 6-aryl 5-cyano 2-thiouracils (1a-1l) were
achieved by the reaction of various aldehydes, ureas, thioureas and ethylcyanoacetate …
achieved by the reaction of various aldehydes, ureas, thioureas and ethylcyanoacetate …
Synthesis and biological value of thiouracils and fused thiouracils (a review)
M Sayed, N Ahmed - Journal of Advanced Pharmacy Research, 2017 - journals.ekb.eg
A literature survey revealed that the thiouracil derivatives and their condensed heterocycles
have occupied a marked position as synthon for various biologically active compounds …
have occupied a marked position as synthon for various biologically active compounds …
[PDF][PDF] Effect of new synthesized compounds of 2-Thiouracil Sulfonamide Derivatives against colon and liver carcinoma cells “In Vitro Study
SM HASSAN, ANA AL-JAF… - International Journal …, 2020 - researchgate.net
Many studies have been focusedon 2-Thiouracil derivatives as an anti-cancer therapy. The
target compounds were prepared to be tested on colon and liver carcinoma cells and …
target compounds were prepared to be tested on colon and liver carcinoma cells and …
Bioassay and bioactivity of polymer as carrier for some active compounds such as anticancer drugs
FM Helaly, AI Khalaf, DEE Nashar, HFA Hamid… - Research on Chemical …, 2014 - Springer
The present work deals with the development of a new slow release polymeric material,
based on maize starch/cellulose acetate blend polymerized with acrylic acid monomer by …
based on maize starch/cellulose acetate blend polymerized with acrylic acid monomer by …
Inhibitory effect of some new uracil and thiouracil derivatives on cercarial penetration enzymes
OA Fathalla, ME Haiba, MM Anwar… - Research on Chemical …, 2013 - Springer
Abstract Some uracil-and thiouracil-5-sulfonohydrazide derivatives have been synthesized
to be evaluated as antischistosomal agents. N-[2-(1, 5-Dimethyl-3-oxo-2-phenylpyrazolin-4 …
to be evaluated as antischistosomal agents. N-[2-(1, 5-Dimethyl-3-oxo-2-phenylpyrazolin-4 …
[CITATION][C] FM Helaly, AI Khalaf, DE El. Nashar, HF Abdel Hamid &
AM Soliman - Res Chem Intermed, 2014