The immunopathogenesis of rheumatoid arthritis (RA) spans decades, beginning with the
production of autoantibodies against post-translationally modified proteins (checkpoint 1) …

Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with
each phase of disease linked to immune cell dysfunction. HLA class II genes confer the …

Rheumatoid arthritis (RA) is an inflammatory disease that begins with a loss of tolerance to
modified self-antigens and immune system abnormalities, eventually leading to synovitis …

Metabolites have functions in the immune system independent of their conventional roles as
sources or intermediates in biosynthesis and bioenergetics. We are still in the pioneering …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

In rheumatoid arthritis (RA), breakdown of self‐tolerance and onset of clinical disease are
separated in time and space, supporting a multi‐hit model in which emergence of …

As a chronic progressive autoimmune disease, rheumatoid arthritis (RA) is characterized by
mainly damaging the synovium of peripheral joints and causing joint destruction and early …

Objective. To analyze the value of neutrophil‐lymphocyte ratio (NLR), platelet‐lymphocyte
ratio (PLR), and lymphocyte‐monocyte ratio (LMR) in the evaluation of disease activity and …

Introduction The incidence of rheumatoid arthritis (RA) and its complications are expected to
increase with age. Remarkably, RA patients were identified features of accelerated aging …

The metabolomics approach represents the last downstream phenotype and is widely used
in clinical studies and drug discovery. In this paper, we outline recent advances in the …