Signal pathways and precision therapy of small-cell lung cancer
M Yuan, Y Zhao, HT Arkenau, T Lao, L Chu… - Signal transduction and …, 2022 - nature.com
Small-cell lung cancer (SCLC) encounters up 15% of all lung cancers, and is characterized
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …
Advances in MicroRNA therapeutics: From preclinical to clinical studies
MicroRNAs (miRNAs) are crucial regulators of gene expression involved in various
pathophysiological processes. Their ability to modulate multiple pathways simultaneously …
pathophysiological processes. Their ability to modulate multiple pathways simultaneously …
[HTML][HTML] A new miRNA-Modified coxsackievirus B3 inhibits triple negative breast cancer growth with improved safety profile in immunocompetent mice
Abstract Coxsackievirus B3 (CVB3) displays great oncolytic activity against various cancer
cells. Previously, we demonstrated that adding targeting sequences (TS) of miR-145/143 …
cells. Previously, we demonstrated that adding targeting sequences (TS) of miR-145/143 …
Coxsackievirus B3—its potential as an oncolytic virus
Oncolytic virotherapy represents one of the most advanced strategies to treat otherwise
untreatable types of cancer. Despite encouraging developments in recent years, the limited …
untreatable types of cancer. Despite encouraging developments in recent years, the limited …
[HTML][HTML] Lung cancer and oncolytic virotherapy——enemy's enemy
Z Li, Z Feiyue, L Gaofeng, L Haifeng - Translational Oncology, 2023 - Elsevier
Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …
A combination of genetically engineered oncolytic virus and melittin-CpG for cancer viro-chemo-immunotherapy
Background Immunotherapy has emerged as an efficient therapeutic approach for cancer
management. However, stimulation of host immune system against cancer cells often fails to …
management. However, stimulation of host immune system against cancer cells often fails to …
[HTML][HTML] MiRNA-Mediated Mechanisms in the Generation of Effective and Safe Oncolytic Viruses
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by
inhibiting the translation of target transcripts. The expression profiles of miRNAs vary in …
inhibiting the translation of target transcripts. The expression profiles of miRNAs vary in …
Development of group B coxsackievirus as an oncolytic virus: opportunities and challenges
H Liu, H Luo - Viruses, 2021 - mdpi.com
Oncolytic viruses have emerged as a promising strategy for cancer therapy due to their dual
ability to selectively infect and lyse tumor cells and to induce systemic anti-tumor immunity …
ability to selectively infect and lyse tumor cells and to induce systemic anti-tumor immunity …
Cancer therapy with the viral and bacterial pathogens: The past enemies can be considered the present allies
Cancer continues to be one of the leading causes of mortality worldwide despite significant
advancements in cancer treatment. Many difficulties have arisen as a result of the …
advancements in cancer treatment. Many difficulties have arisen as a result of the …
Identified GNGT1 and NMU as combined diagnosis biomarker of non‐small‐cell lung cancer utilizing bioinformatics and logistic regression
JJ Zhang, J Hong, YS Ma, Y Shi, DD Zhang… - Disease …, 2021 - Wiley Online Library
Non‐small‐cell lung cancer (NSCLC) is one of the most devastating diseases worldwide.
The study is aimed at identifying reliable prognostic biomarkers and to improve …
The study is aimed at identifying reliable prognostic biomarkers and to improve …