Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

CXCL9, CXCL10, CXCL11, and their receptor (CXCR3) in neuroinflammation and neurodegeneration.

OM Koper, J Kamińska, K Sawicki… - Advances in Clinical …, 2018 - search.ebscohost.com
The aim of this review is to present data from the available literature concerning CXCL9,
CXCL10 and CXCL11, as well as their receptor 3 (CXCR3) in selected diseases of the …

The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity–a tale of conflict and conundrum

M Müller, S Carter, MJ Hofer… - Neuropathology and …, 2010 - Wiley Online Library
M. Müller, S. Carter, MJ Hofer and IL Campbell (2010) Neuropathology and Applied
Neurobiology36, 368–387 The chemokine receptor CXCR3 and its ligands CXCL9 …

The pathogenesis of lyme neuroborreliosis: from infection to inflammation

TA Rupprecht, U Koedel, V Fingerle, HW Pfister - Molecular medicine, 2008 - Springer
This review describes the current knowledge of the pathogenesis of acute Lyme
neuroborreliosis (LNB), from invasion to inflammation of the central nervous system. Borrelia …

Evolution, expression and functional analysis of CXCR3 in neuronal and cardiovascular diseases: a narrative review

D Satarkar, C Patra - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Chemokines form a sophisticated communication network wherein they maneuver the
spatiotemporal migration of immune cells across a system. These chemical messengers are …

High levels of inflammatory chemokines and cytokines in joint fluid and synovial tissue throughout the course of antibiotic‐refractory Lyme arthritis

JJ Shin, LJ Glickstein, AC Steere - Arthritis & Rheumatism, 2007 - Wiley Online Library
Objective To investigate the possible role of chemokines and cytokines in the pathogenesis
of Lyme arthritis. Methods Using cytometric bead array and flow cytometry techniques …

Role of CXCL10 in central nervous system inflammation

D Michlmayr, CS McKimmie - International journal of interferon …, 2014 - Taylor & Francis
The central nervous system (CNS) is a highly complex tissue that is vital for a large number
of life-dependent processes. The neurons of the CNS are post-mitotic and cannot be easily …

CXCL13, CXCL10 and CXCL8 as potential biomarkers for the diagnosis of neurosyphilis patients

C Wang, K Wu, Q Yu, S Zhang, Z Gao, Y Liu, L Ni… - Scientific reports, 2016 - nature.com
At present, diagnosis for neurosyphilis remains a major clinical challenge. Venereal Disease
Research Laboratory (VDRL) titer of the cerebrospinal fluid (CSF) is suboptimally sensitive …

Evaluation of CXCL10, CXCL11, CXCL12 and CXCL13 chemokines in serum and cerebrospinal fluid in patients with tick borne encephalitis (TBE)

J Zajkowska, A Moniuszko-Malinowska… - Advances in medical …, 2011 - Elsevier
Purpose The aim of the study was to assess the concentration of chemokines: CXCL10,
XCL11, CXCL12, CXCL13 in serum and cerebrospinal fluid (CSF) in patients with tick-borne …

Transcriptome assessment of erythema migrans skin lesions in patients with early Lyme disease reveals predominant interferon signaling

A Marques, I Schwartz, GP Wormser… - The Journal of …, 2018 - academic.oup.com
Background The most common clinical manifestation of early Lyme disease is the erythema
migrans (EM) skin lesion that develops at the tick bite site typically between 7 and 14 days …