A primer on the oxDNA model of DNA: when to use it, how to simulate it and how to interpret the results
The oxDNA model of Deoxyribonucleic acid has been applied widely to systems in biology,
biophysics and nanotechnology. It is currently available via two independent open source …
biophysics and nanotechnology. It is currently available via two independent open source …
Structural, mechanical, and thermodynamic properties of a coarse-grained DNA model
We explore in detail the structural, mechanical, and thermodynamic properties of a coarse-
grained model of DNA similar to that recently introduced in a study of DNA nanotweezers …
grained model of DNA similar to that recently introduced in a study of DNA nanotweezers …
Introducing improved structural properties and salt dependence into a coarse-grained model of DNA
We introduce an extended version of oxDNA, a coarse-grained model of deoxyribonucleic
acid (DNA) designed to capture the thermodynamic, structural, and mechanical properties of …
acid (DNA) designed to capture the thermodynamic, structural, and mechanical properties of …
Sequence-dependent thermodynamics of a coarse-grained DNA model
originally designed to reproduce the properties of DNA molecules with average sequences.
The new parametrization introduces sequence-dependent stacking and base-pairing …
The new parametrization introduces sequence-dependent stacking and base-pairing …
An experimentally-informed coarse-grained 3-site-per-nucleotide model of DNA: Structure, thermodynamics, and dynamics of hybridization
A new 3-Site-Per-Nucleotide coarse-grained model for DNA is presented. The model
includes anisotropic potentials between bases involved in base stacking and base pair …
includes anisotropic potentials between bases involved in base stacking and base pair …
Guiding the folding pathway of DNA origami
DNA origami is a robust assembly technique that folds a single-stranded DNA template into
a target structure by annealing it with hundreds of short 'staple'strands,,,. Its guiding design …
a target structure by annealing it with hundreds of short 'staple'strands,,,. Its guiding design …
Coarse-graining DNA for simulations of DNA nanotechnology
To simulate long time and length scale processes involving DNA it is necessary to use a
coarse-grained description. Here we provide an overview of different approaches to such …
coarse-grained description. Here we provide an overview of different approaches to such …
The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics
TE Ouldridge - Natural computing, 2018 - Springer
Improved understanding of molecular systems has only emphasised the sophistication of
networks within the cell. Simultaneously, the advance of nucleic acid nanotechnology, a …
networks within the cell. Simultaneously, the advance of nucleic acid nanotechnology, a …
DNA nanotweezers studied with a coarse-grained model of DNA
We introduce a coarse-grained rigid nucleotide model of DNA that reproduces the basic
thermodynamics of short strands, duplex hybridization, single-stranded stacking, and hairpin …
thermodynamics of short strands, duplex hybridization, single-stranded stacking, and hairpin …
A nucleotide-level coarse-grained model of RNA
We present a new, nucleotide-level model for RNA, oxRNA, based on the coarse-graining
methodology recently developed for the oxDNA model of DNA. The model is designed to …
methodology recently developed for the oxDNA model of DNA. The model is designed to …