Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …

Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Cardiovascular diseases remain the leading cause of death worldwide, with pathological
fibrotic remodeling mediated by activated cardiac myofibroblasts representing a unifying …

Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts
before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins …

Microorganisms form diverse multispecies communities in various ecosystems. The high
abundance of fungal and bacterial species in these consortia results in specific …

Reversible acetylation was initially described as an epigenetic mechanism regulating DNA
accessibility. Since then, this process has emerged as a controller of histone and nonhistone …

Histone acetylation marks are written by histone acetyltransferases (HATs) and read by
bromodomains (BrDs), and less commonly by other protein modules. These proteins …

Acetylation of proteins on lysine residues is a dynamic posttranslational modification that is
known to play a key role in regulating transcription and other DNA-dependent nuclear …

Over the past 10 years, the study of histone acetyltransferases (HATs) has advanced
significantly, and a number of HATs have been isolated from various organisms. It emerged …

Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …