An update on adipose‐derived stem cells for regenerative medicine: where challenge meets opportunity

Y Qin, G Ge, P Yang, L Wang, Y Qiao, G Pan… - Advanced …, 2023 - Wiley Online Library
Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing
attention in the field of regenerative medicine. ADSCs appear to be the most advantageous …

Engineered exosomes and composite biomaterials for tissue regeneration

W Hu, W Wang, Z Chen, Y Chen, Z Wang - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Exosomes, which are small vesicles enclosed by a lipid bilayer and released by many cell
types, are widely dispersed and have garnered increased attention in the field of …

Multifunctional microgel-based cream hydrogels for postoperative abdominal adhesion prevention

B Liu, Y Kong, OA Alimi, MA Kuss, H Tu, W Hu… - ACS …, 2023 - ACS Publications
Postoperative abdominal adhesions are a common problem after surgery and can produce
serious complications. Current antiadhesive strategies focus mostly on physical barriers and …

[HTML][HTML] Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage …

J Tian, W Chen, Y **ong, Q Li, S Kong, M Li, C Pang… - Bioactive Materials, 2023 - Elsevier
Extensive macrophage inflammatory responses and osteoclast formation are predominant
during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small …

Engineering strategies and optimized delivery of exosomes for theranostic application in nerve tissue

Q Li, X Fu, Y Kou, N Han - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Severe injuries or diseases affecting the peripheral and central nervous systems can result
in impaired organ function and permanent paralysis. Conventional interventions, such as …

Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration

J Huang, G Zhang, S Li, J Li, W Wang, J Xue… - Journal of …, 2023 - Springer
Abstract Background Schwann cells (SCs) respond to nerve injury by transforming into the
repair-related cell phenotype, which can provide the essential signals and spatial cues to …

[HTML][HTML] Li–Mg–Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration

Y Sun, H Zhang, Y Zhang, Z Liu, D He, W Xu, S Li… - Bioactive Materials, 2023 - Elsevier
Biomaterials can modulate the local immune and repair-supportive microenvironments to
promote peripheral nerve regeneration. Inorganic bioceramics have been widely used for …

Platelet-rich plasma-derived exosomes boost mesenchymal stem cells to promote peripheral nerve regeneration

Y Zhang, D Yi, Q Hong, J Cao, X Geng, J Liu… - Journal of Controlled …, 2024 - Elsevier
Peripheral nerve injury (PNI) remains a severe clinical problem with debilitating
consequences. Mesenchymal stem cell (MSC)-based therapy is promising, but the problems …

Multi-crosslinked hydrogel built with hyaluronic acid-tyramine, thiolated glycol chitosan and copper-doped bioglass nanoparticles for expediting wound healing

Y Yu, C Wang, Q Fu, Y Wan, A Yu - Carbohydrate Polymers, 2024 - Elsevier
The migration of fibroblasts and endothelial cells is a critical determinant of wound-healing
outcomes for skin injuries. Here, hyaluronic acid-tyramine (HAT) and thiolated glycol …

Differentiated mesenchymal stem cells-derived exosomes immobilized in decellularized sciatic nerve hydrogels for peripheral nerve repair

B Liu, OA Alimi, Y Wang, Y Kong, M Kuss… - Journal of Controlled …, 2024 - Elsevier
Peripheral nerve injury (PNI) and the limitations of current treatments often result in
incomplete sensory and motor function recovery, which significantly impact the patient's …