[HTML][HTML] The road to the ideal stent: A review of stent design optimisation methods, findings, and opportunities

A Kapoor, N Jepson, NW Bressloff, PH Loh, T Ray… - Materials & Design, 2024 - Elsevier
Coronary stent designs have undergone significant transformations in geometry, materials,
and drug elution coatings, contributing to the continuous improvement of stenting success …

Current and future applications of computational fluid dynamics in coronary artery disease

A Candreva, G De Nisco, ML Rizzini… - Reviews in …, 2022 - pmc.ncbi.nlm.nih.gov
Hemodynamics interacts with the cellular components of human vessels, influencing
function and healthy status. Locally acting hemodynamic forces have been associated—by a …

[HTML][HTML] Modelling blood flow in coronary arteries: Newtonian or shear-thinning non-Newtonian rheology?

G De Nisco, ML Rizzini, R Verardi, C Chiastra… - Computer Methods and …, 2023 - Elsevier
Background The combination of medical imaging and computational hemodynamics is a
promising technology to diagnose/prognose coronary artery disease (CAD). However, the …

[HTML][HTML] Mesh neural networks for SE (3)-equivariant hemodynamics estimation on the artery wall

J Suk, P de Haan, P Lippe, C Brune… - Computers in biology and …, 2024 - Elsevier
Computational fluid dynamics (CFD) is a valuable asset for patient-specific cardiovascular-
disease diagnosis and prognosis, but its high computational demands hamper its adoption …

[HTML][HTML] On the nonlinear relationship between wall shear stress topology and multi-directionality in coronary atherosclerosis

HJ Carpenter, MH Ghayesh, AC Zander… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective In this paper we investigate twelve multi-
directional/topological wall shear stress (WSS) derived metrics and their relationships with …

Predicting lipid-rich plaque progression in coronary arteries using multimodal imaging and wall shear stress signatures

G De Nisco, EMJ Hartman, E Torta… - … and Vascular Biology, 2024 - ahajournals.org
BACKGROUND: Plaque composition and wall shear stress (WSS) magnitude act as well-
established players in coronary plaque progression. However, WSS magnitude per se does …

Modelling coronary flows: impact of differently measured inflow boundary conditions on vessel-specific computational hemodynamic profiles

ML Rizzini, A Candreva, C Chiastra, E Gallinoro… - Computer Methods and …, 2022 - Elsevier
Abstract Background and Objectives The translation of hemodynamic quantities based on
wall shear stress (WSS) or intravascular helical flow into clinical biomarkers of coronary …

[HTML][HTML] Coronary artery plaque rupture and erosion: role of wall shear stress profiling and biological patterns in acute coronary syndromes

G Russo, D Pedicino, C Chiastra, R Vinci… - International Journal of …, 2023 - Elsevier
Aims Wall shear stress (WSS) is involved in coronary artery plaque pathological
mechanisms and modulation of gene expression. This study aims to provide a …

Computational fluid dynamics as supporting technology for coronary artery disease diagnosis and treatment: an international survey

C Chiastra, M Zuin, G Rigatelli, F D'Ascenzo… - Frontiers in …, 2023 - frontiersin.org
Background Computational fluid dynamics (CFD) is emerging as an effective technology
able to improve procedural outcomes and enhance clinical decision-making in patients with …

[HTML][HTML] Multiscale multimodal characterization and simulation of structural alterations in failed bioprosthetic heart valves

E Tsolaki, P Corso, R Zboray, J Avaro, C Appel, M Liebi… - Acta biomaterialia, 2023 - Elsevier
Calcific degeneration is the most frequent type of heart valve failure, with rising incidence
due to the ageing population. The gold standard treatment to date is valve replacement …