To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers

GI Al Jowf, ZT Ahmed, RA Reijnders, L de Nijs… - International journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …

Chronic pain and chronic stress: two sides of the same coin?

CG Abdallah, P Geha - Chronic Stress, 2017 - journals.sagepub.com
Pain and stress share significant conceptual and physiological overlaps. Both phenomena
challenge the body's homeostasis and necessitate decision-making to help animals adapt to …

The sense of self in the aftermath of trauma: Lessons from the default mode network in posttraumatic stress disorder

RA Lanius, BA Terpou… - European journal of …, 2020 - Taylor & Francis
Trauma can profoundly affect the sense of self, where both cognitive and somatic
disturbances to the sense of self are reported clinically by individuals with posttraumatic …

Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach

TJ Akiki, CL Averill, KM Wrocklage, JC Scott, LA Averill… - Neuroimage, 2018 - Elsevier
Disruption in the default mode network (DMN) has been implicated in numerous
neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However …

Synaptic loss and the pathophysiology of PTSD: implications for ketamine as a prototype novel therapeutic

JH Krystal, CG Abdallah, LA Averill, B Kelmendi… - Current psychiatry …, 2017 - Springer
Abstract Purpose of Review Studies of the neurobiology and treatment of PTSD have
highlighted many aspects of the pathophysiology of this disorder that might be relevant to …

Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

EL Dennis, SG Disner, N Fani, LE Salminen… - Molecular …, 2021 - nature.com
A growing number of studies have examined alterations in white matter organization in
people with posttraumatic stress disorder (PTSD) using diffusion MRI (dMRI), but the results …

The effects of trauma on brain and body: A unifying role for the midbrain periaqueductal gray

BA Terpou, S Harricharan… - Journal of …, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD), a diagnosis that may follow the experience of trauma,
has multiple symptomatic phenotypes. Generally, individuals with PTSD display symptoms …

Homeostatic normalization of alpha brain rhythms within the default-mode network and reduced symptoms in post-traumatic stress disorder following a randomized …

AA Nicholson, M Densmore, PA Frewen… - Brain …, 2023 - academic.oup.com
Collective research has identified a key electroencephalogram signature in patients with
post-traumatic stress disorder, consisting of abnormally reduced alpha (8–12 Hz) rhythms …

Neuroimaging correlates of resilience to traumatic events—a comprehensive review

J Bolsinger, E Seifritz, B Kleim, A Manoliu - Frontiers in psychiatry, 2018 - frontiersin.org
Improved understanding of the neurobiological correlates of resilience would be an
important step toward recognizing individuals at risk of develo** post-traumatic stress …

[HTML][HTML] Classifying heterogeneous presentations of PTSD via the default mode, central executive, and salience networks with machine learning

AA Nicholson, S Harricharan, M Densmore… - NeuroImage: Clinical, 2020 - Elsevier
Intrinsic connectivity networks (ICNs), including the default mode network (DMN), the central
executive network (CEN), and the salience network (SN) have been shown to be aberrant in …