Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion

P Makvandi, M Kirkby, ARJ Hutton, M Shabani… - Nano-Micro Letters, 2021 - Springer
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

2D and 3D electrospinning technologies for the fabrication of nanofibrous scaffolds for skin tissue engineering: A review

A Keirouz, M Chung, J Kwon… - Wiley …, 2020 - Wiley Online Library
This review provides insights into the current advancements in the field of electrospinning,
focusing on its applications for skin tissue engineering. Furthermore, it reports the …

Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

[HTML][HTML] Insights into the mechanics of solid conical microneedle array insertion into skin using the finite element method

W Shu, H Heimark, N Bertollo, DJ Tobin… - Acta Biomaterialia, 2021 - Elsevier
In order to develop optimum microneedle designs, researchers must first develop robust,
repeatable and adaptable test methods which are representative of in vivo conditions …

Skin preparation–free, stretchable microneedle adhesive patches for reliable electrophysiological sensing and exoskeleton robot control

H Kim, J Lee, U Heo, DK Jayashankar, KC Agno… - Science …, 2024 - science.org
High-fidelity and comfortable recording of electrophysiological (EP) signals with on-the-fly
setup is essential for health care and human-machine interfaces (HMIs). Microneedle …

Microneedle-based insulin transdermal delivery system: current status and translation challenges

J Zhao, G Xu, X Yao, H Zhou, B Lyu, S Pei… - Drug Delivery and …, 2022 - Springer
Diabetes mellitus is a metabolic disease manifested by hyperglycemia. For patients with
type 1 and advanced type 2 diabetes mellitus, insulin therapy is essential. Subcutaneous …

Drug delivery with dissolving microneedles: Skin puncture, its influencing factors and improvement strategies

X **u, G Gao, Y Liu, F Ma - Journal of Drug Delivery Science and …, 2022 - Elsevier
Over the past decades, the use of microneedles, a unique transdermal drug delivery
technology, to deliver drugs to the skin for biological effects has been very active, and the …

Recent advances in skin-like wearable sensors: Sensor design, health monitoring, and intelligent auxiliary

Z Huang, Y Xu, Y Cheng, M Xue, M Deng… - Sensors & …, 2022 - pubs.rsc.org
When entering old age, the tissue structure of the body begins to age, the functions of
various organs appear disordered, resistance declines and is prone to various geriatric …

Evaluation of the antibacterial properties of iron oxide, polyethylene glycol, and gentamicin conjugated nanoparticles against some multidrug-resistant bacteria

FM Abdulsada, NN Hussein, GM Sulaiman… - Journal of Functional …, 2022 - mdpi.com
Antibacterial resistance is observed as a public health issue around the world. Every day,
new resistance mechanisms appear and spread over the world. For that reason, it is …

[HTML][HTML] Viscoelastic constitutive artificial neural networks (vCANNs)–A framework for data-driven anisotropic nonlinear finite viscoelasticity

KP Abdolazizi, K Linka, CJ Cyron - Journal of Computational Physics, 2024 - Elsevier
The constitutive behavior of polymeric materials is often modeled by finite linear viscoelastic
(FLV) or quasi-linear viscoelastic (QLV) models. These popular models are simplifications …