Atomoxetine restores the response inhibition network in Parkinson's disease

CL Rae, C Nombela, PV Rodríguez, Z Ye, LE Hughes… - Brain, 2016 - academic.oup.com
Parkinson's disease impairs the inhibition of responses, and whilst impulsivity is mild for
some patients, severe impulse control disorders affect∼ 10% of cases. Based on preclinical …

White matter microstructure alterations in idiopathic restless legs syndrome: a study combining crossing fiber-based and tensor-based approaches

Y Xue, S **e, X Wang, X **, C Liu - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Restless legs syndrome (RLS) is a common sensorimotor disorder
characterized by an irrepressible urge to move the legs and frequently accompanied by …

Hypothesizing music intervention enhances brain functional connectivity involving dopaminergic recruitment: common neuro-correlates to abusable drugs

K Blum, T Simpatico, M Febo, C Rodriquez… - Molecular …, 2017 - Springer
The goal of this review is to explore the clinical significance of music listening on
neuroplasticity and dopaminergic activation by understanding the role of music therapy in …

A kinder, gentler dopamine… highlighting dopamine's role in behavioral flexibility

JA Beeler, R Cools, M Luciana, SB Ostlund… - Frontiers in …, 2014 - frontiersin.org
If dopamine were a politician, it might have an image problem. The organizing metaphor for
dopamine function is reward. Implicit in this formulation is that a system that drives appetitive …

Role of dopamine D2 receptors in optimizing choice strategy in a dynamic and uncertain environment

S Kwak, N Huh, JS Seo, JE Lee, PL Han… - Frontiers in Behavioral …, 2014 - frontiersin.org
In order to investigate roles of dopamine receptor subtypes in reward-based learning, we
examined choice behavior of dopamine D1 and D2 receptor-knockout (D1R-KO and D2R …

Neuromodulation of Dopamine D2 Receptors Alters Orbitofrontal Neuronal Activity and Reduces Risk-Prone Behavior in Male Rats with Inflammatory Pain

M Dourado, H Cardoso-Cruz, C Monteiro… - Molecular …, 2025 - Springer
Dopamine (DA) is believed to play a crucial role in maintaining the integrity of the rodent
orbitofrontal cortex (OFC) networks during risk-based decision-making processes. Chronic …

Drug abuse relapse rates linked to level of education: can we repair hypodopaminergic-induced cognitive decline with nutrient therapy?

K Blum, SJ Schoenthaler, M Oscar-Berman… - The Physician and …, 2014 - Taylor & Francis
It is well known that athletes and other individuals who have suffered painful injuries are at
increased risk for all reward deficiency syndrome (RDS) behaviors, including substance use …

Syn3 gene knockout negatively impacts aspects of reversal learning performance

A Moore, J Linden, JD Jentsch - Eneuro, 2021 - eneuro.org
Behavioral flexibility enables the ability to adaptively respond to changes in contingency
requirements to maintain access to desired outcomes, and deficits in behavioral flexibility …