Conventionally it is taught that all cellular membranes are freely permeable to water and that
net movements of water between cells and their surrounding interstitial fluid are determined …

All mammalian cells live in the aqueous medium, yet for many cell biologists, water is a
passive arena in which proteins are the leading players that carry out essential biological …

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The interactions between mathematics and physiology have a long and illustrious history, of
which the study of calcium signalling is but a small chapter. Nevertheless, for those involved …

The distribution of charged membrane-permeable molecular probes between intracellular
organelles, the cytoplasm, and the outside medium is governed by the relative membrane …

An equation for membrane voltage is derived that takes into account the electrogenicity of
the Na/K pump and is valid dynamically, as well as in the steady state. This equation is …

The ability of all cells to set and regulate their size is a fundamental aspect of cellular
physiology. It has been known for sometime but not widely so, that size stability in animal …

The presence of impermeant molecules within a cell can lead to an increase in cell volume
through the influx of water driven by osmosis. This phenomenon is known as the Donnan (or …

The ability to regulate cell volume in the face of osmotic challenge is one of the most
fundamental of cellular homeostatic mechanisms. Cellular and Molecular Physiology of Cell …

All animal cells are surrounded by a flexible plasma membrane that is permeable to water
and to small ions. Cells thus face a fundamental problem: the considerable tension that their …