Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review

CI Chukwuma, MG Matsabisa, MA Ibrahim… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Diabetes and hypertension are pathophysiologically
related diseases that co-exist with a wider complex of metabolic diseases having similar set …

Reduction of blood glucose by plant extracts and their use in the treatment of diabetes mellitus; discrepancies in effectiveness between animal and human studies

BL Furman, M Candasamy, SK Bhattamisra… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance The global problem of diabetes, together with the limited
access of large numbers of patients to conventional antidiabetic medicines, continues to …

A comprehensive review on zinc (II) complexes as anti-diabetic agents: The advances, scientific gaps and prospects

CI Chukwuma, SS Mashele, KC Eze… - Pharmacological …, 2020 - Elsevier
Zinc has gained notable attention in the development of potent anti-diabetic agents, due to
its role in insulin storage and secretion, as well as its reported insulin mimetic properties …

[HTML][HTML] Quercetin and/or Ascorbic Acid Modulatory Effect on Phenobarbital-Induced Slee** Mice Possibly through GABAA and GABAB Receptor Interaction …

R Hossain, K Al-Khafaji, RA Khan, C Sarkar, MS Islam… - Pharmaceuticals, 2021 - mdpi.com
Depressive disorder is a recurrent illness that affects large numbers of the general
population worldwide. In recent years, the goal of depression treatment has moved from …

Antioxidant, antidiabetic, and anti-inflammatory activities of flavonoid-rich fractions of Solanum anguivi Lam. fruit: In vitro and ex vivo studies

AB Ojo, IG Adanlawo - Heliyon, 2024 - cell.com
Diabetes mellitus is a major, rapidly growing endocrine disorder in most countries. The high
cost and side effects of conventional drugs for the management of this disease have shifted …

[HTML][HTML] Phenolic enriched fraction of Clerodendrum glandulosum Lindl. leaf extract ameliorates hyperglycemia and oxidative stress in streptozotocin-nicotinamide …

P Khound, PK Deb, S Bhattacharjee, KD Medina… - Journal of Ayurveda and …, 2024 - Elsevier
Abstract Background Clerodendrum glandulosum Lindl. is an important ethnomedicinal
shrub of Northeast India, used by traditional healers to control various ailments like diabetes …

Vernonia Amygdalina Del. stimulated glucose uptake in brain tissues enhances antioxidative activities; and modulates functional chemistry and dysregulated …

OL Erukainure, OA Oyebode, CU Ibeji… - Metabolic brain …, 2019 - Springer
Brain glucose uptake is usually reduced in type 2 diabetes owing to downregulation of brain
glucose transporters. The ability of Vernonia amygdalina to stimulate glucose uptake as well …

Raffia palm (Raphia hookeri G. Mann & H. Wendl) wine modulates glucose homeostasis by enhancing insulin secretion and inhibiting redox imbalance in a rat model …

OL Erukainure, OA Oyebode, OM Ijomone… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Raffia palm (Raphia hookeri) wine (RPW) is
amongst the natural products from plants, utilized singly or in combination with other …

Oxidative testicular injury: effect of l-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways

OL Erukainure, O Atolani, P Banerjee, R Abel, OJ Pooe… - Amino Acids, 2021 - Springer
The antioxidant and anti-proinflammatory activities of l-leucine were investigated on
oxidative testicular injury, ex vivo. In vitro analysis revealed l-leucine to be a potent …

[HTML][HTML] Therapeutic efficacy of polyphenol-rich fraction of Boesenbergia rotunda in diabetic rats: a focus on hypoglycemic, antihyperlipidemic, carbohydrate …

T Wang, C Liu, S Shu, Q Zhang… - Frontiers in Bioscience …, 2022 - imrpress.com
Introduction: Boesenbergia rotunda is a famous culinary/medicinal herb native to Southeast
Asia region and it is traditionally used in the treatment of several diseases. This study …