Abstract WormBase (www. wormbase. org) is the central repository for the genetics and
genomics of the nematode Caenorhabditis elegans. We provide the research community …

GTF (Gene Transfer Format) and GFF (General Feature Format) are popular file formats
used by bioinformatics programs to represent and exchange information about various …

Among bone-material qualities, mineralization is pivotal in conferring stiffness and
toughness to the bone. Osteomalacia, a disease ensuing from inadequate mineralization of …

The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …

Genomic analyses are sensitive to contamination in public databases caused by incorrectly
labeled reference sequences. Here, we describe Conterminator, an efficient method to …

Haemonchus contortus is a globally distributed and economically important gastrointestinal
pathogen of small ruminants and has become a key nematode model for studying …

Genome assemblies are currently being produced at an impressive rate by consortia and
individual laboratories. The low costs and increasing efficiency of sequencing technologies …

Motile and non-motile cilia are associated with mutually-exclusive genetic disorders. Motile
cilia propel sperm or extracellular fluids, and their dysfunction causes primary ciliary …

The de Bruijn graph is a key data structure in modern computational genomics, and
construction of its compacted variant resides upstream of many genomic analyses. As the …

With the advent of long-read sequencing, previously unresolvable genomic elements are
being revisited in an effort to generate fully complete reference genomes. One such element …