[HTML][HTML] Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner… - Physiological …, 2015 - journals.physiology.org
The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
Neuromuscular junction formation, aging, and disorders
Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
Molecular mechanisms contributing to the development of beef sensory texture and flavour traits and related biomarkers: Insights from early post-mortem muscle using …
Beef sensory quality comprises a suite of traits, each of which manifests its ultimate
phenotype through interaction of muscle physiology with environment, both in vivo and post …
phenotype through interaction of muscle physiology with environment, both in vivo and post …
[HTML][HTML] When actin is not actin'like it should: a new category of distinct primary immunodeficiency disorders
EGG Sprenkeler, SDS Webbers… - Journal of innate …, 2021 - karger.com
An increasing number of primary immunodeficiencies (PIDs) have been identified over the
last decade, which are caused by deleterious mutations in genes encoding for proteins …
last decade, which are caused by deleterious mutations in genes encoding for proteins …
The Actin Filament-Binding Protein Coronin Regulates Motility in Plasmodium Sporozoites
KS Bane, S Lepper, J Kehrer, JM Sattler… - PLoS …, 2016 - journals.plos.org
Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter
host cells. Here we show that the actin filament-binding protein coronin regulates gliding …
host cells. Here we show that the actin filament-binding protein coronin regulates gliding …
Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders
Introduction: Signal transduction at the neuromuscular junction (NMJ) is compromised in a
diverse array of diseases including myasthenia gravis, Lambert-Eaton myasthenic …
diverse array of diseases including myasthenia gravis, Lambert-Eaton myasthenic …
Heart-specific DNA methylation analysis in plasma for the investigation of myocardial damage
Background Circulating cell-free DNA (cfDNA) can be released when myocardial damage
occurs. Methods Here, we used the methylated CpG tandem amplification and sequencing …
occurs. Methods Here, we used the methylated CpG tandem amplification and sequencing …
Nerve-independent formation of membrane infoldings at topologically complex postsynaptic apparatus by caveolin-3
HLR Kwan, ZCK Chan, X Bi, J Kutkowska… - Science …, 2023 - science.org
Junctional folds are unique membrane specializations developed progressively during the
postnatal maturation of vertebrate neuromuscular junctions (NMJs), but how they are formed …
postnatal maturation of vertebrate neuromuscular junctions (NMJs), but how they are formed …
Myasthenia gravis: from the viewpoint of pathogenicity focusing on acetylcholine receptor clustering, trans-synaptic homeostasis and synaptic stability
M Takamori - Frontiers in Molecular Neuroscience, 2020 - frontiersin.org
Myasthenia gravis (MG) is a disease of the postsynaptic neuromuscular junction (NMJ)
where nicotinic acetylcholine (ACh) receptors (AChRs) are targeted by autoantibodies …
where nicotinic acetylcholine (ACh) receptors (AChRs) are targeted by autoantibodies …
Structure of Toxoplasma gondii coronin, an actin‐binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress
J Salamun, JP Kallio, W Daher… - The FASEB …, 2014 - Wiley Online Library
Coronins are involved in the regulation of actin dynamics in a multifaceted way, participating
in cell migration and vesicular trafficking. Apicomplexan parasites, which exhibit an actin …
in cell migration and vesicular trafficking. Apicomplexan parasites, which exhibit an actin …