Radiotherapy should have low toxicity in the entrance channel (normal tissue) and be very
effective in cell killing in the target region (tumour). In this regard, ions heavier than protons …

Cancer therapy with accelerated charged particles is one of the most valuable biomedical
applications of nuclear physics. The technology has vastly evolved in the past 50 years, the …

Carbon ion therapy is a promising evolving modality in radiotherapy to treat tumors that are
radioresistant against photon treatments. As carbon ions are more effective in normal and …

Simple Summary Carbon ion radiotherapy offers ballistic and radiobiological advantages
over conventional photon-based radiotherapy, making it an effective option in case of rare …

Background The aim of this study is to evaluate results in terms of local control (LC), overall
survival (OS), and toxicity profile and to better identify factors influencing clinical outcome of …

Simple Summary Skull-base chordomas (SBC) are rare tumours with unfavourable
outcomes, even when undergoing advanced treatments such as carbon-ion radiotherapy …

In radiotherapy, radiation-quality should be an expression of the biological and physical
characteristics of ionizing radiation such as spatial distribution of ionization or energy …

Carbon ion radiotherapy (CIRT) is develo** toward a versatile tool in radiotherapy;
however, the increased relative biological effectiveness (RBE) of carbon ions in tumors and …

This position paper, led by the NRG Oncology Particle Therapy Work Group, focuses on the
concept of relative biologic effect (RBE) in clinical proton therapy, with the goal of providing …

Applied nuclear physics is an essential part of the research activity at many particle
accelerators. New, large accelerator facilities are currently under construction in Europe …