From C-reactive protein to interleukin-6 to interleukin-1: moving upstream to identify novel targets for atheroprotection

PM Ridker - Circulation research, 2016 - Am Heart Assoc
Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP)
predict vascular risk with an effect estimate as large as that of total or high-density …

ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic) a …

AT Hirsch, ZJ Haskal, NR Hertzer, CW Bakal… - circulation, 2006 - Am Heart Assoc
It is important that the medical professions play a significant role in critically evaluating the
use of diagnostic procedures and therapies in the detection, management, and prevention of …

Heart disease and stroke statistics—2012 update: a report from the American Heart Association

Writing Group Members, VL Roger, AS Go… - Circulation, 2012 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Heart disease and stroke statistics—2011 update: a report from the American Heart Association

VL Roger, AS Go, DM Lloyd-Jones, RJ Adams… - Circulation, 2011 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Elevated C-reactive protein levels in overweight and obese adults

M Visser, LM Bouter, GM McQuillan, MH Wener… - Jama, 1999 - jamanetwork.com
ContextHuman adipose tissue expresses and releases the proinflammatory cytokine
interleukin 6, potentially inducing low-grade systemic inflammation in persons with excess …

Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women

PM Ridker, JE Buring, J Shih, M Matias… - Circulation, 1998 - Am Heart Assoc
Background—C-reactive protein (CRP) predicts risk of myocardial infarction (MI) and stroke
among apparently healthy men, but in women, virtually no data are available. Methods and …

High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease

PM Ridker - Circulation, 2001 - Am Heart Assoc
Inflammation plays a major role in atherothrombosis, and measurement of inflammatory
markers such as high-sensitivity C-reactive protein (HSCRP) may provide a novel method …

Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein (a), and standard cholesterol screening as …

PM Ridker, MJ Stampfer, N Rifai - Jama, 2001 - jamanetwork.com
ContextSeveral novel risk factors for atherosclerosis have recently been proposed, but few
comparative data exist to guide clinical use of these emerging biomarkers. ObjectiveTo …

Peripheral arterial disease in people with diabetes

American Diabetes Association - Diabetes care, 2003 - search.proquest.com
Peripheral arterial disease (PAD) is a condition characterized by atherosclerotic occlusive
disease of the lower extremities. On May 7-8, 2003, a Consensus Development Conference …