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Genetics of human primary hypertension: focus on hormonal mechanisms
W Manosroi, GH Williams - Endocrine reviews, 2019 - academic.oup.com
Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …
the individual causes (diseases) having a common sign—an elevated blood pressure. To …
When blood pressure refuses to budge: exploring the complexity of resistant hypertension
MK Champaneria, RS Patel, TL Oroszi - Frontiers in cardiovascular …, 2023 - frontiersin.org
Resistant hypertension, defined as blood pressure that remains above goal despite using
three or more antihypertensive medications, including a diuretic, affects a significant …
three or more antihypertensive medications, including a diuretic, affects a significant …
A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population
Y Takahashi, K Yamazaki, Y Kamatani, M Kubo… - Scientific Reports, 2021 - nature.com
Numerous genetic variants associated with hypertension and blood pressure are known, but
there is a paucity of evidence from genetic studies of resistant hypertension, especially in …
there is a paucity of evidence from genetic studies of resistant hypertension, especially in …
Managing resistant hypertension: focus on mineralocorticoid-receptor antagonists
Mineralocorticoid-receptor antagonists (MRAs) have proven to be effective in some types of
hypertension, especially in resistant hypertension (RHTN). In this phenotype of …
hypertension, especially in resistant hypertension (RHTN). In this phenotype of …
Excessive dietary sodium intake and elevated blood pressure: a review of current prevention and management strategies and the emerging role of …
OM Dong - BMJ nutrition, prevention & health, 2018 - pmc.ncbi.nlm.nih.gov
INTRODUCTION Precision medicine has the potential to improve current standard of care
for patients, especially in the cardiovascular field. Better prevention and treatment of …
for patients, especially in the cardiovascular field. Better prevention and treatment of …
Resistant hypertension: new insights and therapeutic perspectives
LM Ruilope, E Rodríguez-Sánchez… - European Heart …, 2020 - academic.oup.com
Resistant hypertension (RH) is a concept that currently goes beyond the classical definition
of blood pressure≥ 140/90 mmHg in subjects receiving three or more drugs of different …
of blood pressure≥ 140/90 mmHg in subjects receiving three or more drugs of different …
[HTML][HTML] Gene polymorphisms of the renin-angiotensin-aldosterone system as risk factors for the development of in-stent restenosis in patients with stable coronary …
This study investigated the renin-angiotensin-aldosterone system (RAAS) gene
polymorphisms as possible genetic risk factors for the restenosis development in patients …
polymorphisms as possible genetic risk factors for the restenosis development in patients …
Resistant or refractory hypertension: are they different?
Resistant hypertension (RHTN) consists in a condition where blood pressure (BP) levels
remain uncontrolled despite the use of at least three drugs or if the control happens with four …
remain uncontrolled despite the use of at least three drugs or if the control happens with four …
Genetics of resistant hypertension: a novel pharmacogenomics phenotype
Resistant hypertension (RHTN), defined as an uncontrolled blood pressure despite the use
of multiple antihypertensive medications, is an increasing clinical problem associated with …
of multiple antihypertensive medications, is an increasing clinical problem associated with …
Association of mineralocorticoid receptor polymorphism I180V with left ventricular hypertrophy in resistant hypertension
OBJECTIVES Genetic polymorphisms on mineralocorticoid receptor gene (NC3C2) are
associated with variability of mineralocorticoid receptor (MR) function and cardiovascular …
associated with variability of mineralocorticoid receptor (MR) function and cardiovascular …