Ursolic acid and its derivatives as bioactive agents

S Mlala, AO Oyedeji, M Gondwe, OO Oyedeji - Molecules, 2019 - mdpi.com
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …

A review on mechanistic insight of plant derived anticancer bioactive phytocompounds and their structure activity relationship

K Mazumder, A Aktar, P Roy, B Biswas, ME Hossain… - Molecules, 2022 - mdpi.com
Cancer is a disorder that rigorously affects the human population worldwide. There is a
steady demand for new remedies to both treat and prevent this life-threatening sickness due …

Triterpenes as potentially cytotoxic compounds

M Chudzik, I Korzonek-Szlacheta, W Król - Molecules, 2015 - mdpi.com
Triterpenes are compounds of natural origin, which have numerously biological activities:
anti-cancer properties, anti-inflammatory, anti-oxidative, anti-viral, anti-bacterial and anti …

Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents

H Chen, Y Gao, A Wang, X Zhou, Y Zheng… - European journal of …, 2015 - Elsevier
Currently, there is a renewed interest in common dietaries and plant-based traditional
medicines for the prevention and treatment of cancer. In the search for potential anticancer …

Therapeutic potential of ursonic acid: comparison with ursolic acid

J Son, SY Lee - Biomolecules, 2020 - mdpi.com
Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is
a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as …

Therapeutic potential of ursolic acid in cancer and diabetic neuropathy diseases

M Alam, S Ali, S Ahmed, AM Elasbali, M Adnan… - International journal of …, 2021 - mdpi.com
Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants,
having numerous pharmacological effects. UA and its analogs treat multiple diseases …

Therapeutic potential of demethylzeylasteral, a triterpenoid of the genus Tripterygium wilfordii

X Sun, B Shen, H Yu, W Wu, R Sheng, Y Fang, R Guo - Fitoterapia, 2022 - Elsevier
Pentacyclic triterpenoids are important natural products widely presenting in nature with rich
bioactivities. Tripterygium wilfordii Hook. f., a precious Chinese medicinal material, is used to …

Triterpenoids

RA Hill, JD Connolly - Natural Product Reports, 2017 - pubs.rsc.org
Covering: 2013. Previous review: Nat. Prod. Rep., 2015, 29, 1028–1065 This review covers
the isolation and structure determination of triterpenoids reported during 2013 including …

Plant-derived terpenoids: a promising tool in the fight against melanoma

P Kłos, D Chlubek - Cancers, 2022 - mdpi.com
Simple Summary Despite the numerous therapies, melanoma remains the deadliest of all
skin cancers; however, plant-derived terpenoids are defense molecules that have proven …

[HTML][HTML] Sorbus intermedia (EHRH.) PERS. fruits as a novel source of biologically active triterpenoids–Comparative studies of ursolic acid derivatives with cytotoxic …

A Sołtys, A Galanty, P Zagrodzki, K Grabowska… - Biomedicine & …, 2022 - Elsevier
In the current study, the fruits of a popular ornamental tree, Sorbus intermedia, were
investigated phytochemically and biologically as potential source of bioactive triterpenes …